1908. | Innervation in Vaso-motor Reflexes, etc. 355 
the cord is cut in the lumbar region, so that the limbs are deprived of vaso- 
dilator supply, there is no dilatation in them when a second dose of!strychnine. 
is given. But the strongest evidence is the behaviour of the “dilator ” animal. 
\ 
" val \ 
h } nl at A 
‘sau agi ery i fr iG eat iy" 
Agni mu 
Fic. 10.—Action of a dose of strychnine subsequent to the first. Upper curve, volume 
of intestine (Cat). Lower curve, arterial pressure. Time-in 10 sec. 
a 
Here the jirst dose produces fall of pressure and vaso-dilatation (figs. 11 and 12). 
In fig. 12 the fall of pressure is preceded by a small rise. In both these cases 
| ( oa ae wT ANd ii 
ui 7 
Fic. 11.—Effect of first dose in “dilator” Fie. 12.—As fig. 11, but hind-leg in place 
animal. Upper curve, volume of ear. of ear. 
Lower curve, arterial pressure. 
the organ under observation was deprived of its constrictor supply, so that the 
increase of volume must be due to excitation of dilators. The drug, in fact, 
excites both dilators and constrictors indiscriminately, the effect on the 
VOL. LXXX.—B. 2 ¥ 
