366 Dr. W. M. Bayliss. On Reciprocal [Jan. 20, 
kidney. In the third curve, ether was resumed and the median excited 
before complete recovery; there was a diphasic effect in both kidney and 
blood-pressure—the latter had risen to 88 mm. before the excitation was 
made. 
This experiment shows that the fall of blood-pressure obtained from 
sensory nerves under chloroform is caused by dilatation of arterioles, but does 
not decide whether this is due to inhibition of constrictors or to excitation of 
dilators. This point is only to be settled by observing the effect on an organ, 
AKAMA 
AANA 
VAAN M IN N MV Ai Avaya, 
wie ANAM AAAR 
Fia. 24.—Action of chloroform on result of excitation of median on blood-pressure and 
on kidney. Upper curves, volume of kidney. Lower curves, arterial pressure. 
Zero is not the same in the three tracings, see text. First tracing, before 
chloroform. Second, under full influence of the drug. Third, after partial 
recovery. 
such as the leg, in which the dilators have been cut. Since the results are 
much more easily interpreted when the passive effects are reduced to a 
minimum by evisceration, it is necessary first to describe the action of 
chloroform in the “dilator” animal. Now, a similar fate befell my early 
experiments with this drug to that of the analogous experiments with 
strychnine ; I lost several by pushing the chloroform to total abolition of all 
vascular reflexes in the vain attempt to obtain a depressor effect from the 
median nerve. Although it seems difficult to believe, I can see no other 
alternative but to interpret the rise of arterial pressure seen under maximal 
