452 Drs. S. M. Copeman and H. W. Hake. [June 19, 
Table C—continued. 
Period of Digestion, one hour and a-half. 
(a) Over 12 months. (6) Under 3 months. 
Series 11. Feb. 4, 1908. | Series 15. Feb. 11,1908. | Series 13. Feb. 7, 1908. Res 18. Feb. 25, 1908. 
No. of Hydro- No. of Hydro- No. of | Hydro- No. of | Hydro- 
stomachs. | chloric acid. | stomachs. | chloric acid. | stomachs. | chloric acid. | stomachs. | chloric acid. 
6 0°1515 it 0°1575 6 0 -2002 12 0°1716 
i: 0 -2310 4, 0 °1673 2 0 1894. é 
if 0 *2643 2 0 1684: Ht 0 °1929 
6 0 -2110 4, 0 °2085 
8 0 1755 (av.) | 18 0 1869 (av.) 13 | 0 °2005 (av.) | 12 0 °1716 (av.) 
and 0°1683. All these mice were under three months. The nature of the 
tumours is indicated in the note to Table D. 
Apparently in the experiments relating to mice with transplanted tumours, 
the greater proportion have attained a maximum at the one-hour period of 
digestion. 
Comparing the general results both for normal mice and for mice with 
transplanted tumours, it is obvious that there is no general tendency to 
a decrease in the latter as regards secretion of hydrochloric acid, the 
variations in both cases being strictly comparable, and, in fact, if we take 
the average of all mice examined in the two classes, we find that for periods 
of digestion of one hour and of one hour and a-half, 245 normal mice gave an 
average of 0°1546 per cent., while 290 mice with transplanted tumours during 
the same periods of digestion gave an average of 0°1673 per cent., that is 
a slight increase. Again, in the experiments made without reference to time 
of digestion (Table A), 150 normal mice gave an average of 01121, and 
178 mice with transplanted tumours gave an average of 0°1752. 
Only quite recently we have had the opportunity of examining a series of 
rat stomachs also supplied by Dr. Bashford, and as these varied in weight 
(after one hour’s digestion) from 2°5 to over 10 grammes, it was a com- 
paratively easy matter, and obviously advantageous, to analyse them singly. 
We examined 15 such stomachs after one hour’s digestion, three from rats 
which had been inoculated from tumours identified at the Imperial Cancer 
Research Laboratories as Flexnor 158 and 15a, and four from rats which 
had been inoculated from a tumour known as Jensen 8a. 
