454 Drs. S. M. Copeman and H. W. Hake. [June 19, 
Table E shows a brief summary of the results obtained in both series. 
Table E.—Percentages of Physiologically Active Hydrochloric Acid in 
Stomachs of Rats with Transplanted Tumours (positive), and in Normal 
tats (negative); 1 hour’s digestion. 
Series 26. May 19, 1908. 
eam Hydrochloric acid. Pan Hydrochloric acid. 
(a) Positive. (b) Negative. 
1 0°1143 i 0 °1192 
1 0 °2276 1 0 °1076 
1 0 °2574 Hl: 0 °1400 
al 0 °1835 1 0 °1358 
1 0 °1164 i 0 °1564 
Hl 0 °2047 1 01975 
1 0 °1822 
7 01887 (av.) _ 6 0 +1427 (av.) 
It will be seen from the figures given in Table E that for one hour’s 
digestion the rats with transplanted tumours gave an average of 0:1837 per 
cent. of hydrochloric acid, while those in which result of attempted 
transplantation had been negative, and which may therefore be regarded 
as normal, gave an average for the same period of digestion of 0°1427 per 
cent. The variations from the average are in neither series very considerable. 
_ Finally, we may refer to the examination between May, 1906, and May, 
1908, of 15 stomachs of mice affected with tumours which, though 
undoubtedly cancer, were of entirely spontaneous origin. For these, again, 
we are indebted to Dr. Bashford. 
The following Table F gives a summary of the results obtained. 
It will be seen from an inspection of this table that the amount of 
hydrochloric acid in the gastric contents of mice with spontaneous tumours 
varied (with one exception, viz., 0°0961 per cent., January 18, 1908) 
between 01372 and 0:2627, with a total average for 15 stomachs of 
0:1929 per cent. 
Conclusions.—Allowing for individual variations, so unavoidable in physio- 
logical experiments, it may fairly be argued that under exactly similar 
conditions of feeding and of periods of digestion there was evidently no 
general tendency to decrease in the secretion of hydrochloric acid by mice, 
either with transplanted or spontaneous tumours (and, so far as our 
