1908.| Hydrochloric Acid in the Gastric Contents in Cancer. 455 
Table F.—Percentage of Physiologically Active Hydrochloric Acid in the 
Stomachs of Mice with Spontaneous Tumours. 
Date. | No. of stomachs. Hydrochloric acid. 
Period of Digestion, uncertain. 
May 29, 1906......... | 1 0 °2286 
Nov. 4, 1907....:.... | 1 0 +1847 
INO; vo, 1907... .....<1 1 0 :1872 
Nov. 8, 1907.. ...... | 1 0 1652 
INiov..26,, 1907.....5.:. | 4 0 °2136 
Jan. 18, 1908........ | 1 0 :0961 
Jan. 18, 1908......... | 1 0 +1856 
Period of Digestion, 14 hours. 
Biebs 25, 1908... .c.086: | it | O 2627 
Period of Digestion, 1 hour. 
May 18, 1908;......:. | 1 0 °2132 
May 18; 1908s: 4.2.<.. | a 0 °1634 
May, 18 -1908- 5.2... | 1 0 °2120 
May U8, 1908. -.<..... | 1 0 *1903 
General average <j..jcteessicce asec +60 0 -1929 
experiments go, the same would appear to be the case with rats), 
but on the contrary, we found a distinct tendency towards increase of 
the hydrochloric acid. 
Consequently it would appear that the conclusion arrived at by Moore 
and others, that a marked diminution or even an absence of free hydrochloric 
acid occurs in the gastric contents in malignant disease of organs other 
than the stomach in human beings, is certainly not borne out by the results 
of our investigations on the amount of physiologically active hydrochloric 
acid present in the stomach contents of mice suffering from cancer. 
(5) Heperiments made on the Human Subject. (Examination of 
Test-meals.) 
In the absence of determinations of hydrochloric acid in the gastric 
contents of man, by the same methods that we had employed in our work 
on mice, it did not seem possible to arrive at any satisfactory comparison of 
the results which we have set out in this paper, with those of Moore and his 
fellow-workers. This being so, it appeared to us to be a matter of importance 
to carry out a series of estimations on patients suffering from undoubtedly 
