On the Experimental Treatment of Trypanosomiasis. 477 
They note that this inflammatory reaction at times failed to occur, and in 
this our results agree. 
~The conclusion at which the observers named arrive is that the subcu- 
taneous tissues of the guinea-pig are peculiarly sensitive to adrenal grafts, 
whichiproduce in them cedema and hemorrhagic solution. 
It is difficult, however, to eliminate here the possibility that the results 
are due to auto-bacterial infection. 
The organs of normal guinea-pigs abound in various forms of bacteria, 
the growth of which is inhibited under natural conditions. When necrosis 
is set up by the adrenal graft or by the injection of an extract, the dead 
tissues furnish a nidus in which the latent pathogenic micro-organisms may 
grow. 
Further Results of the Experimental Treatment of Try- 
panosomiasis : being a Progress Report to a Committee of the 
Royal Socvety. 
By H. G. Purer, F.L.S., and H. R. Bateman, Captain R.A.M.C. 
(Communicated by J. Rose Bradford, M.D., F.R.S. Received August 25, 1908.) 
The following results are a continuation of the work of which summaries 
have already appeared in the ‘ Proceedings of the Royal Society.’* 
The experiments have been carried out with the same strains of Nagana 
and Surra as were used before. 
A.—Condition of the Animals living at the Date of the Completion of the Tables 
wn the last Paper. : 
Table I1—Nagana Rats treated with Atoxyl and Succeoninide of Mercury. 
(Average duration of untreated disease, 5°5 days.) 
No. 4 died on the 307th day after inoculation. 
ead sy 365th . 
ak) i 249th i, 
ee Gs) i 188th F 
a zall 5 63rd 
Of these, No. 15, which was apparently cured, was used on the 147th day 
after inoculation for re-inoculation, with the view of ascertaining if any 
- immunity had been conferred. This was found not to be the case.t 
* B, vol. 79, 1907, pp. 505—516, and B, vol. 80, 1908, pp. 1—12. 
+ Vide ‘ Roy. Soc. Proc.,’ B, vol. 80, p. 10. 
