1908. | Hem-agglutinins, etc., i the Blood. 535 
degree of agglutination when added to normal red cells. There was no 
auto-agelutination, and normal serum did not react when added to the 
immune red cells of this case. 
In another example of pulmonary tuberculosis, the immune serum did not 
react when mixed with normal red cells or with the red cells from the same 
case, but normal serum produced a high degree of agglutination when mixed 
with the tuberculous red cells. 
The agglutinative properties from seven cases of acute pneumonia and 
two cases of acute pneumococcic empyema were subjected to a detailed 
examination, and, as some of the results were of interest, they may be 
expressed concisely and briefly :— 
The serum from one case of. acute pneumonia when added to the red cells 
from the same case gave no result, but when added to normal red cells a 
high degree of agglutination occurred. When this pneumococcic serum was 
diluted with salt solution and added to normal red cells, employing dilutions 
of 1:20 and 1: 200, no agglutination took place. 
Another case of acute pneumonia gave results of similar interest. The 
blood was obtained from a patient suffering from acute pneumonia just after 
the crisis. The immune red cells and the immune serum when mixed, failed 
to react, but when the immune red cells were mixed with normal serum, or 
when the immune serum was added to normal red cells, a high degree of 
agelutination resulted. The serum from this case was also mixed with the 
patient’s unwashed red cells ; the result was similar to that obtained with the 
washed red cells. The immune serum from the second case of acute 
pneumococcic empyzema produced very slight agglutination when mixed with 
the immune red cells. Normal serum gave a similar result with these red 
cells, but the immune serum in the presence of normal red cells, and of the 
red cells from another case of acute pneumococcic empyema, produced 
considerable agglutination ; in fact, the clumps reached an enormous size, and 
there were very few free red cells present. 
In the blood obtained from a case of long standing epilepsy, a striking 
instance of auto-agglutination was observed. The patient’s serum, when 
added to his own red cells, caused a high degree of agglutination. The same 
effect was observed when the immune serum was added to normal red blood 
corpuscles. In this specimen of blood we have one of the few examples, and 
yet one of the most striking instances of auto-agglutination. 
In another case of long standing epilepsy the immune serum failed to react 
in the presence of the immune red cells or normal red cells, but when normal 
serum was mixed with the immune red cells, they collected together into 
large and tight clumps. 
