36 



62. ; Woods, C. W. ; and McHaffey, D. G. 1972. Chemosterilants against 

 the boll weevil. 1. Aziridines. J. Econ. Entomol. 65: 1543-1547. 



Of 141 aziridinyl compounds tested against Anthonomus grandis Boheman, 56 

 had sterilizing activity when added to the insect diet. The most reliable 

 indicator of effectiveness was a reduction in oviposition that persisted when 

 treated males were crossed with untreated females. The most effective com- 

 pounds were substituted bisCl-aziridinyl) phosphine oxides and sulfides, 

 but the relatively high activity of substituted 1-aziridineethanols and other 

 compounds indicated that the structure-activity relationships determined for 

 this class of sterilants in the house fly, Musca domestica L., were not 

 applicable to A. grandis . 



63. ; Woods, C. W.; and Terry, P. H. 1978. Boll weevil: chemosterilization 

 by fumigation and dipping. J. Econ. Entomol. 71: 862-866. 



A procedure suitable for sterilizing both sexes of Anthonomus grandis grandis 

 Boheman on a large scale was developed. First, the weevils were fumigated with 

 bisazir (P,P-bis(l-aziridinyl)-N-methylphosphinothioic amide, AI3-61585) at atmo- 

 spheric pressure for 90 min, and 30 min later, they were dipped for 5 sec into a 

 1.35% solution of penfluron (2,6-difluoro-N-[ [ [4-trif].uoromethyl) phenyljamino] 

 carbonyl]benzamide, AI3-63223) in acetone. In either sex, the sterility exceeded 

 "59%,- and 59.3% of the treated males survived 10 days posttreatment. A new labo- 

 ratory-size fumigation chamber with a rotating bisazir-treated paddle was design- 

 ed and scaled up to a field-size chamber suitable for treating up to 200,000 

 weevils at a time. Monitoring of the sterilizing treatment consisted of 

 measuring the concentration of bisazir vapors during the fumigation and 

 analyzing the treated weevils for residues of bisazir and penfluron. One 

 day posttreatment, no residues of bisazir or of its aziridinyl -.etabolite 

 could be detected in the treated weevils, but penfluron residues decreased 



