1867.] 



ExtiYicfive Matters of Urine. — Part I. 



1.23 



previously obtained, and serves to show that the composition of the 

 extractive matters does not vary viith. the source whence they are derived, 



H (1863). 



In order to remove any doubt that might still have remained in regard 

 to the composition of the urinary extractive matters, I made another series 

 of experiments, employing for this purpose ordinary healthy urine. The 

 urine was mixed as usual with acetate of lead, and then with basic acetate, 

 but the precipitate with the latter was alone made use of. This, after 

 being w^ashed with water, was treated in the manner before described, and 

 yielded as usual a substance soluble in ether («), a second soluble in 

 alcohol but insoluble in ether (b), a third insoluble in a mixture of alcohol 

 and ether (c), and a fourth insoluble both in alcohol and in ether (d). 

 The first of these was treated with water, which left a quantity of fatty 

 matter undissolved. To the filtered liquid there was added acetate of lead ; 

 and having been again filtered, it was mixed with a large quantity of 

 alcohol, which produced a precipitate of the usual appearance. The 

 analysis of this precipitate yielded the following results : — 



I. 1*0945 grm. gave 0'8540grm. carbonic acid and 0*2115 grm. water. 

 1*5585 grm. gave 0'12G5grm. chloride of platinum and ammonium. 

 0*6600 grm. gave 0*5255 grm. sulphate of lead. 

 In 100 parts it contained therefore 



C 21*28 



H 2*14 



N 0-50 



17*50 



PbO 58*58 



100*00 



The substance combined with oxide of lead contained, in 1 00 parts, 



C 51*37 



H 5*16 



N..... 1*20 



42*27 



100 00 



If this composition be compared with that yielded by Analysis III. Series 

 A, it will be seen that the difference between them is not greater, even as 

 regards the amount of oxide of lead, than is usually found in two analyses 

 of the same substance. This near approximation! n the results of the first 

 and the concluding series of experiments, as far as regards one of the ex- 

 tractive matters, is remarkable. 



The substances h and c, though probably one and the same, were 

 examined separately, in order to remove all doubt as to the identit}^ of 

 their composition. The former was treated with absolute alcohol, in which 

 it was entirely soluble. To the solution there was added a little acetate of 

 lead, and the dark-brown precipitate produced by the latter having been 



K 2 



