1867.] 



Extractive Matters of Urine. — Part II. 



131 



easy comparison with one another, and the theoretical composition, will 

 show* : — 









A. III. 



F. I. 



a. I. 



H. I. 







Calculation. 



2_ 



1. 



1, 2, 3. 



2. 



Mean. 



c . . 



. 516 



5175 



51*04 



50-65 



51-88 



51-37 



51-23 





, . 51 



5-11 



5-43 



5-67 



5-25 



5-16 



5-38 



N . 



. 14 



1-40 



1-34 



1-22 



1-27 



1-20 



1-26 



O50. 



. 416 



4174 



42-19 



42-46 



41-60 



42-27 



42-13 





997 



100-00 



100-00 



100-00 



100-00 



100-00 



100-00 



I do not insist very strongly on the correctness of this formula ; since, 

 for a body the atomic weight of which is so high, and was determined 

 solely by the amount of nitrogen contained in it, other formulse might be 

 calculated agreeing equally well with the results of analysis. I have 

 adopted this one in preference, because a sim.ple relation is thereby esta- 

 blished between the composition of this extractive matter and that of the 

 other, as I shall presently show. It will, however, hardly be doubted 

 that the composition of this substance is, under all circumstances, the 

 same, seeing that the material employed for its preparation in these expe- 

 riments was derived from various sources, at wide intervals of time, and 

 that it was obtained on one occasion from the precipitate with neutral 

 acetate of lead, on other occasions from that with basic acetate of lead, or 

 from all the three lead precipitates combined. 



The second analysis corresponds more closely with the formula CyglTjgNOj^ 

 than with the one just given, as I have before remarked. This proves 

 that the substance has a tendency to take up the elements of water, a ten- 

 dency still further developed in the case of the specimen employed for the 

 Analysis V. Series F, which led to the formula Cgg H59 NO^g. 



In order to avoid circumlocution I shall for the future call this substance 

 urian. 



The extractive matter soluble in alcohol but insoluble in ether was in 

 my opinion obtained only on one occasion free from all admixture, and in 

 the state in which 1 suppose it to exist originally in the urine. On this 

 occasion its composition corresponded with the formula C33 H.,^ NO^^, as 

 proved by the results of Analysis III. Series F, which were as follows : — 



^38 



N 



0„. 



Calculation. 



F. III. 

 2. 



228 46-24 



46-44 



27 5-47 



5-66 



14 2-83 



3-16 



224 45-46 



44-74 



493 100-00 



100-00 



In this and the follo-wing Tables the numerals 1, 2, and 3 denote that the deter- 

 mination was made with substance obtained either from the precipitate produced in 

 urine with neutral acetate of lead (1), or from that with basic acetate of lead in the 

 liquid filtered from the first precipitate (2), or from the precipitate with ammonia in the 

 filtrate from the other two precipitates (3). When the three numerals occur together, 

 it indicates that all three precipitates were employed in the manner described in Part I. 



