No. 494] NOTES AND LITERATURE 



143 



Experiments in Transplanting Limbs and their Bearing upon the 

 Problem of Development of Nerves.— Students of nerve regenera- 

 tion are divided into two camps according 1 as they view the in- 

 fluence of the central or ganglion cell on the regeneration of 

 peripheral nerve fibers. On the one hand it is assumed that 

 no regeneration can take place in peripheral nerves that are 

 isolated from their ganglion cell. On the other hand it is 

 assumed that regeneration can take place in the complete ab- 

 sence of central influence. This is often spoken of as "auto- 



The latter view finds its most recent exponent in Dr. Braus, 

 of Heidelberg, who was led to it by the results obtained in 

 transplantation experiments. lie found that either the trans- 

 planted limb contained no nerves at all. or that functional nerves, 

 typical in their distribution, were developed trom any region of 

 the body, whence they must have arisen in situ and secondarily 



interest. Young tadpoles 

 penetrated to the limb buds 

 to other regions of the body 

 in this bizarre position, qu 

 its parts, including its nei 

 cessfully grafted on the hei 

 no nerves had been present 

 tation. and as it seemed inc< 

 for example, could grow ir 



cells and fibers of the 

 "aneurogenic" indiv 

 and once again devel 

 were absent. If the. 

 find these limbs inne 

 particular region. 



Professor K. G. II 

 invaluable service in 



