958 



In a memoir on the Iguanodon and Hylasosaurns (Phil. Trans. 

 1849), Dr. Mantell states that he had been able to obtain slices of 

 one of these spines for microscopical examination, and that their in- 

 ternal structure was identical with that of the acknowledged dermal 

 scutes of the same reptile. Still the true form of the articulating 

 surface of the base of these spines was unknown, every specimen 

 being imperfect in this respect. At length, after the lapse of eighteen 

 years, Dr. Mantell obtained, through the liberality of ^Iv. Peter Fuller 

 of Lewes, from the very Cjuarry in which the original specimen of 

 Hylceosaurus was found, the spine figured and described in this 

 communication, in which the ba?e is sufficiently entire to show that 

 the mode of implantation in the skin was identical with that of the 

 true dermal scutes ; thus confirming the author's original interpreta- 

 tion of these remarkable appendages having constituted a serrated 

 crest along the back of the Hyl^osaurus. The specimens, and the 

 microscopical sections, were exhibited to the Society. 



4. " On the Variations of the Sulphates and Phosphates in the 

 Urine in Disease." By Henry Bence Jones, M.D., F.R.S. 



The object of the paper is to show whether the sulphates in the 

 urine are increased or diminished in any class of diseases. The 

 corresponding variations of the phosphates were determined. The 

 particular conclusions may be thus stated : — 



1. In three cases of acute chorea the most remarkable increase 

 was observed in the amount of sulphates in the urine. In the same 

 cases the quantity of urea was very much increased. The quantity 

 of urine made in twenty- four hours was not excessively diminished, 

 and the total amount of earthy and alkaline phosphates was below 

 the average amount, sometimes remarkably less than in health. 



2. In delirium tremens and in other delirium a remarkable in- 

 crease in the amount of sulphates in the urine was frequently ob' 

 served, and the total amount of phosphates was in the same cases 

 occasionally remarkably diminished ; and the resemblance to the 

 state of chorea was still closer, inasmuch as occasionally a very great 

 excess of urea was found in these cases also. 



3. In acute inflammatory affections of the nervous structures, du- 

 ring the most febrile symptoms, an increase vras observed in the 

 amount of sulphates in the urine ; and the total amount of earthy and 

 alkaline phosphates in these diseases was increased in the same pro- 

 23ortion as the sulphates were increased. 



4. In some slight and chronic diseases of the nervous structures 

 no increase in the amiount of sulphates in the urine was observed, 

 excepting when sulphate of magnesia had been taken. 



5. In acute diseases, in which neither the nervous nor the muscular 

 structures were chiefly affected, no increase in the sulphates or 

 phosphates was observed, except after sulphate of magnesia. 



6. In chronic diseases, in which neither the nervous nor the mus- 

 cular structures were chiefly affected, no decided increase in the 

 sulphates or phosiDhates in the urine was observed, except after 

 sulphate of magnesia. One case of exostosis may be regarded as a 

 doubtful exception to this statement. 



