Mettam — Studies in Tuberculosis. 



69 







A.M. 



P.M. 



October 



1 



105-6 



1060 



> ' 



2 



104-0 



106-2 



) > 



3 



104-2 



105-6 



>) 



4 



104-2 



105-8 



>> 



5 



104-0 



104-8 



)) 



6 



104-6 



1050 



)) 



7 



104-8 



104-6 



)j 



8 



104-0 



105-0 



>» 



9 



104-4. 



Killed. 



It will be observed that, save on two occasions — on September 26 

 and October 7 — the evening temperature was higher than the 

 morning temperature. 



Post-mortem Examination. — There was a local lesion where inocu- 

 lation had been first attempted, and smears made from it revealed the 

 tubercle bacilli. Sections showed an enormous proliferation of 

 connective tissue around the vein, obliterating it. Caseation had 

 commenced. Tubercle bacilli in enormous numbers were found in 

 the new tissues. The anterior lobes of both lungs showed diffused 

 broncho -pneumonia ; the lung-tissue being extensively hepatised. The 

 lesion in the right lung was more extensive than that in the left. The 

 lymphatic glands on the thoracic trachea (tracheal or bronchial) and 

 the post-mediastinal lymphatic glands were greatly enlarged, and con- 

 tained tubercle bacilli. The spleen, the liver, and kidneys were normal 

 in appearance to the naked eye. No lesions could be discovered in the 

 mesenteric glands ; nor were there any appreciable lesions in the 

 cervical lymphatic glands. Examined microscopically, the lungs 

 revealed acute tuberculous broncho-pneumonia. Numerous tubercles, 

 evidently primary tubercles, developed in the pulmonary capillaries 

 were present, as well as alveolar tubercles which had developed 

 secondarily. The alveoli contained well-developed tubercles, in 

 addition to a certain amount of fibrin, red blood-corpuscles, and isolated 

 leucocytes. The alveolar tubercles contained giant cells, and tubercle 

 bacilli were readily found. Microscopic examination of the spleen, 

 liver, and kidneys, demonstrated the presence of young tubercles, as did 

 also examination of the bronchial and mediastinal lymphatic glands. 

 The results of the post-mortem and microscopic examination are 

 similar to the results obtained from the rabbit after infection by the 

 auricular vein, although in the bovine the lesions in the abdominal 

 viscera are not so pronounced. 



