No. 638] INTEBNAL SECRETIONS OF AMPHIBIA XS 203 



phosed. It is interesting to note that while tadpoles of 

 Rana sijh atica aie killed h\ a 5 drops lodme solution and 

 upon a 3-drops-iodine solution respond promptlv with 

 development ot the hmd limbs, the larvir of J. nxinilnl inn 

 showed no other effect from a 5-drops solution tli.iii a 

 slightly decreased food intake. The latter ci iciunst.ince 

 may account tor the longer duration ot the l;ir\al ]M i-iod 

 ot the experimental larva\ Siiicc ii was lidicx cd that m 

 this experiment the solution was too weak. - tar\:f (»t the 

 same species, atter a short so)ouni m a .;-(lro]ts >olu:i,m, 



II shows, in this experiment also niciainorniio-is \va> not 

 aeceleiatcd b\ the lodme solution \ ( i il ]n\i wne 

 led directly crystals ot lodnie to make sure that the in- 

 effectiyeness ot the lodme solution in salamanders was not 

 due to a possible impermeability ot the larval skin tor 

 iodine. In one case two crvstal-ted larva^ metanior- 

 phoscd at 124 da\s ^^lll, ih, .ontiol m. t inn i i.lio^ .1 it 

 the age of 101 da\s hi inotli. i < xp. i nn n in unu i \ 

 larva? were employed, one iiictaniofplioxMi at the auv ot 

 M)daxs, whik the contiols nut unoipho^Ml , -n.i,,. 

 Of the t\N0 otlKi lana, om <li(l n. l liou n,x ^ _n ot 

 metamorphosis when it was killed tor liisiolouical ex- 

 amination: tlu^ other one died ti'(»ni an overdose ot lodme, 

 but did not show aii\- siuii ot nietaiiiorphosis. 



