INHERITANCE OF CONGENITAL PALSY IN 

 GUINEA-PIGS 1 



PROFESSOR LEON J. COLE 

 University of Wisconsin, and 

 DR. HEMAN L. IBSEN 

 Kansas State Agricultural College 

 CONTENTS 



Introductory. 



Origin of Palsied Stock. 



Inheritance of the Palsy Character. 



Etiology. 

 Discussion 

 Pigeon. 



Mouse and Rat. 



Rabbit. 



Guinea-pig. 



Sheep. 



Man. 

 Summary. 

 References. 



Introductory 



In 1914 a litter of two guinea-pigs was born in our lab- 

 oratory, one of winch differed from the other in that it 

 appeared to lack nervous control. When this individual 

 was placed on its feet, attempts on its part to walk re- 

 sulted in spasmodic stiffening of the legs, causing it to 

 fall over on its side, where it lay helpless and unable to 

 get up. Although the animal appeared otherwise in good 

 physical condition, it was thought at the time that the 

 trouble might be due to temporary nutritional disurbance, 

 and attempts were accordingly made to feed it by hand, 



i Papers from the Department of Genetics, Agricultural Experiment Sta- 

 tion, University of Wisconsin, No. 18. Published with the approval of the 

 Director of the Station. 



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