No. 610] ALCOHOL AND WHITE MICE 605 



second generation of alcohol mice outgrew all and con- 

 tinued ahead until the end of the experiment. After the 

 sixth week there were rather wide variations and this con- 

 tinued as long as they were weighed. At the eighth week 

 the weights of the different lines stood in the following 

 order: second generation of alcohol mice 15.1 grams; 

 female alcohol mice 14.3 grams; male alcohol mice 13.6 

 grams ; the double alcohol mice 13 grains ; and the controls 

 11.6 grams. In my former experiments ('11) the alcohol 

 young surpassed the controls in the rate of growth. 



Comparison of the Different Lines 



The control line had the fewest young of any of the 

 lines ; they had no deaths from lack of vitality ; the growth 

 of their young was slower than that of any of the other 

 lines except the female alcohol line. 



The male alcohol line was more fecund than the con- 

 trols, but less so than the other alcohol lines ; their death 

 rate from lack of vitality was four mice or 6 per cent. ; the 

 growth of their young was better than that of the controls 

 and female alcohol lines. 



The female alcohol mice were the most fecund of all the 

 lines; their death rate was four mice or 9.8 per cent.; 

 their growth was even slower than the control mice until 

 the last week, when they made a large gain and outgrew 

 all but the second generation of alcohol mice. 



The double alcohol mice were slightly less fecund than 

 the female alcohol line ; five mice or 6.8 per cent, of their 

 young died ; they grew a little faster than the controls. 



For the second generation of alcohol mice, two males, 

 offspring of the male alcohol line, were mated with two 

 females, young of the same line and one female from the 

 female alcohol line. Thus one grandmother and all but 

 one of the grandfathers were alcoholized, the second gen- 

 eration were all alcoholized after they became adult and 

 one from birth and their young also were alcoholized. 

 The fecundity of the second generation of alcohol mice 

 was high ; they had one death from lack of vitality, or 4 



