causing Disease in Man in Nyasaland. 185 



Table III — continued. 









Period of 



Duration 





.Date. 



No. of 



Source of virus. 



incubation, 



of disease, 



Remarks. 





expt. 





in days. 



1 



in days.* 











Dog. 







Mar. 28... 



2033 



Naturally infected 



p 



p 



Died April 1 . 



May 14... 



2156 



From Rat 2091 



15 



A t\ 



4U 



JJiecl oi fetrain 111. 



„ 14... 



2157 



209 J 



8 



33 



J) 33 



„ 14... 



2158 



2091 



8 



26 



3) 33 



„ 14... 



2159 



„ 2091 



15 



93 



33 33 



„ 14... 



2160 



2091 



15 



102 



33 33 







Ayerage 



12 -2 



58 -8 









Guinea-pig. 







Mnr 28 



2039 



From Dog 2033 







XI C T CI 3UU » CU. 11 > 1 >ii UUDUIIICBi 



28... 



2040 



„ 2033 







33 33 



May 21... 



2180 



From Eat 2089 



22 



— 



Recovered. 



„ 21... 



21S1 



2089 







Never showed trypanosomes. 









Eat. 







Mar. 28... 



2037 



From Dog 2033 1 



13 



73 



Died of Strain III. 



Apr. 16... 



2089 



From Rat 2037 



5 



15 



JJ 33 



,, 16... 



2090 



2037 



5 



87 



33 33 



„ 16... 



2091 



2037 





28 



33 33 



May 14... 



2167 



2091 



8 



57 





Oct. 23... 



2426 



From Guinea-pig 2180 





19 











7-8 



46-5 





* Duration includes the days of incubation ; it dates from the day of inoculation. 



Disease set up in various Animals by the Trypanosome causing Disease in Man 

 in Nyasaland. The Naturally Infected Dog Strain. 



Ox. — This trvpanosome does not appear to be virulent to the ox. Tour 

 experiments were made. The trypanosomes appeared in the blood of one of 

 the oxen, and it was returned as " Eecoyered " after being under observation 

 for 335 days. The parasites were only seen on three occasions in this ox, 

 and then only in scanty numbers. 



Goat. — The trypanosome also has little effect on goats. Twenty-one were 

 inoculated. Of these 12 proved refractory; five showed the trypanosomes 

 in their blood on one or two occasions in very scanty numbers, and were 

 returned as " Eecovered " after being under observation for nearly a year ; 

 four died, one from the result of an accident, two from pneumonia, and the 

 remaining one only once showed the trypanosomes, and as no post-mortem 

 examination was made it is impossible to say what was the cause of 

 death. It may therefore be said that not a single goat of the 21 died of the 

 disease. 



