Action of Carbon Dioxide and Adrenalin on the Heart. 379 



Table III. — Venous Pressures. 



Temp. 



B.P. 



I.V.C. 



L.A. 



Bate 

 10 sees. 



Output 

 10 sees. 



Output beat. 



— . 



Experiment 1 (23.10.13). — Dog. 6"1 kgrm., heart weight 55 grm. 













c.c. 



c.c. 



35° C. 



126 



260 



500 



22 



189 



8-6 





1 c.c. adrenalin, 1/10000. 











162 



18 



45 



34 



232 



6-8 





132 



14 



11 



'37 



207 



5 6 





130 



10 



18 



37 



192 



5 2 





130 



20 



40 



34 



189 



5 - 5 5 per cent. C0 2 . 





1 c.c. adrenalin + 8 per cent. C< 









135 



16 



30 



38 



200 



5-2 





Experiment 1 



i.-Dog, 



7 - 2 kgrm., heart weight 60 grm. 



35 -5° C. 



92 



200 



54 



32 



313 



9 75 





1 c.c. adrenalin, 1/10000. 











92 



200 



| 14 



41 



263 



6-4 





Experiment 3 



— Dog, 6*45 kgrm., heart weight 44 grm. 



36 -3 d C. 



106 



190 





25 



172 



6 9 





"5 c.c. adrenalin, 1/10000. 









• 



106 



30 





35 5 



190 



5 3 





108 



40 





34 5 



200 



5-8 8 per cent. C0 2 . 





Experiment 4. 



— Dog, 5-5 kgrm., heart weight 46 - 5 grm. 



35 -2° C. 



95 



10 





28 



110 



3-9 





95 



40 





22 -5 



106 



4 -7 11 per cent. CO*. 





95 



10 





26 



106 



4 -0 





-5 c.c. adrenalin, 1/10000. 











94 









37 5 



98 



2-6 





94 



40 





26 "5 



100 



3 -8 20 per cent. C0 2 . 





Experiment 5. — Dog, 3 kgrm., heart weig 



tit 33*5 grm. 



33° C. 



130 



330 



- 



15 



85 







1 c.c. adrenalin, 1/10000. 











130 



330 





24 



77 



3 2 





125 



380 





21 



62 



2 -95 7 per cent. C0 2 on. 



Experiments with Cats. — Various difficulties were encountered in making 

 the experiments on cats, the main ones being due to the sensitiveness of 

 the lungs. The blood of several cats had to be used in order to get 

 sufficient to fill the tubes of the schema, and it seemed that the foreign 

 blood was liable to cause oedema of the lungs, which soon brought the 

 experiment to a conclusion. A typical example of the results obtained in 

 a good experiment is given in Table IV, from which it will be seen that 

 with various percentages of C0 2 no increase in the output per minute was 

 obtained, while the heart rate is reduced considerably by the larger per- 

 centages. In other experiments, using the suck and thrust pump devised 



