542 



Messrs. J. Barcroft and T. Kato. 



Time. 



Kate of blood How m 



Oxygen per grm. 



Exudation in c.c. 



c.c. per min. 



per min. 



per min. 



Before commencement of 









stimulation — 









10 min 



4-6 



'0052 



0-05 



During stimulation, calcu- 









lated from commence- 









ment — 









3 min 



6-7 



0-016 



0-17 



15 min 



30 



0-04 



0-33 



After stimulation, calcu- 









lated from cessation of 









stimulus — 











20 



0-012 



0-28 







U \Ju 4 



KJ OJ_ 



1 hr. 40 min 



30 



0-012 



0-15 



2 hr. 25 min 



20 



0-013 





3 hr. 30 min 



17 



012 



0-08 



4 hr. 47 min 



15 



0-004 



(0 -02) 



6 hr. min 



15 



-002 



(0 -oo) 



7 hr. 45 min 



8-5 



0-004 



0-07 



Figures in hrackets are inside the range of experimental error. 



In order to ascertain how much of the observed exudation was retained 

 in the muscle, the muscle was weighed at the end of the experiment, i.e., 

 8 h. 15 m. after the stimulus ceased. The muscle on the opposite side was 

 also weighed, its nerve having been cut 8 h. 30 m. previously. 



grm. 



(A) "Weight of stimulated muscle 38*2 



(B) „ unstimulated muscle 3T6 



Approximate quantity of fluid retained 6"2 or 19 p.c. of (B). 



The muscles were also weighed in Einger's solution, with the result that 

 their specific gravities relatively to Kinger's solution were — 



(A) Sp. gr. of stimulated muscle 1*061 



(B) „ unstimulated muscle 1'070 



This difference in the specific gravity makes it clear that the difference in 

 weight of the stimulated muscle was not to be accounted for by a difference 

 in the original size of the stimulated muscle or a greater quantity of 

 blood in it. 



The observations on exudation, oxygen intake, and blood are typical of 

 other experiments, except in so far as the effects do not always last so long, 

 the minimal period of hypersemia being two hours. 



ii. The Submaxillary Gland. 

 In most experiments pilocarpine has been used as a stimulant. 



