On Rabies. 



one case of street rabies, in a part of the cervical portion of the cord 

 I found this so extensive as to obliterate nearly the whole of the gray 

 substance for some length of the cord, the haemorrhage becoming dis- 

 tinctly organised, with the formation of vessels or channels ; I have 

 found similar appearances in other parts of the cord in different cases, 

 but none so extensive as this. These seem to originate in the vessels 

 running in the anterior fissure, in which clots forming thrombi are 

 often apparent, presenting the appearances figured by Gowers 

 (' Pathol. Soc. Trans.,' vol. 28, 1876-77, p. 10, &c), though frequently 

 of greater extent proportionately to the size of the vessel. Extensive 

 extravasation and, in stained preparations, much granular matter is 

 always apparent, the formation presenting every appearance of being 

 caused by microparasites : in. the majority of cases I have been unable 

 to demonstrate their presence, from causes mentioned below, but in 

 some few sections, as described, I haye clearly found the microbes in 

 the pericellular and perivascular lymph spaces, aceompanied by 

 appearances of embolism, and extravasation in the capillaries of their 

 immediate neighbourhood. The occurrence of these haemorrhages in 

 different situations, involving the roots of different sets of spinaL 

 nerves, will obviously affect the symptoms of paralysis according to 

 the muscles supplied by the nerves involved. 



In the alimentary canal and respiratory organs conspicuous changes 

 are constantly present. The tongue is generally dry and discoloured, 

 often brown ; the epiglottis is frequently conspicuously injected, 

 the lower part of the larynx so deeply congested as to appear crimson. 

 This often involves the greater portion of the trachea and extends to 

 the bronchi, the lungs are generally congested, though to a variable 

 extent, most usually they are bright red, with portions deeply injected, 

 very frequently on the margins of the lower lobes ; parts of them 

 sometimes are consolidated and livid. Though some of these changes 

 may be due to causes independent of rabies, congestion however is 

 most usually present : oedema I have not found. 



The pharynx and oesophagus less freqnently show congestion than 

 the trachea, but the stomach, as generally remarked, shows very con- 

 stant and typical changes ; in every case, excepting one, in the dog, I 

 have found it devoid of solid food ; in that case, as in every other 

 excepting one, it has contained some hay ; in the greater number of 

 the cases of street rabies there have also been found other foreign 

 substances — cinders, coal, wood, cloth, &c. In cases, however, of ex- 

 perimental inoculation, a dog confined in a cage throughout the course 

 of the disease can have but little opportunity of eating any indigestible 

 substances, excepting hay and straw. 



The stomach frequently contains a thick, dark-brown fluid, which 

 is also found in the duodenum ; the mucous membrane if not dis- 

 coloured by the fluid present, is usually redder than normally; con- 



