524 



Mr. G. S. Johnson. 



Platinum and Gold Salts of Kreatinins from Urinary Kreatin. 



When a solution of tabular kreatinin, prepared from urinary 

 kreatin by Liebig's process, and which has re- crystallised in the tabular 

 form from cold aqueous solution, is acidulated with hydrochloric 

 acid, mixed with aqueous solution of platinic chloride and evaporated 

 in vacuo over sulphuric acid, a crystalline platinum salt is formed. 

 The crystals are paler in colour than the platinum salt of the tabular 

 kreatinin of urine, and require nearly twice as much water to dissolve 

 them. The salt is easily purified by washing away the excess of 

 platinic chloride from it with strong alcohol, and then re- crystallising 

 from watery solution. 



Like the platinum salt of the kreatinin of urine, it contains two 

 molecules of water of crystallisation. 



0162 gram of the salt became opaque at 100° C, losing O009 gram 

 of water. 



This corresponds with 5*55 per cent. 



The formula 2{C 4 H 7 N 3 O.HCl}PtCl 4 .2H 2 requires 5*34 per cent. 



Comparison between the Platinum Salts of Tabular Kreatinin cl of 

 Urine and Tabular Kreatinin a from the Urinary Kreatin, as 

 regards solubility in Water. 



"Weight of 

 solution (in 

 grams) satu- 

 rated at 15° C. 



Name of salt taken. 



Weight of 

 dried at 

 100° c. 



Parts by weight 

 of water which 

 dissolve 1 part 

 of salt at 10° C. 



9-837 



Platinum salt of tabular 



Ka 













0-652 



14-1 



3-641 



Platinum salt of tabular 











from urinary kreatin . . 





0-143 



24-4 



Thus the platinum salt of the natural kreatinin is nearly twice as 

 soluble in water as that of the artificial base. 



Neither the efflorescent kreatinin of urine, nor the efflorescent 

 kreatinin from urinary kreatin form platinum salts of any definite 

 nature. After treatment with alcohol the crystalline matter which 

 remains upon spontaneous evaporation of mixed chlorides is found to 

 be a mixture of a little yellow granular matter with transparent 

 colourless needles, probably the hydrochloride of the kreatinin. 



With auric chloride, however, the efflorescent kreatin, and also the 

 tabular anhydrous kreatinin from urinary kreatin, give fine gold salts, 

 having the formula C 4 H 7 N 3 O.HCl 4 .AuCl 3 , and crystallising in thin 

 yellow lustrous plates. 



The gold salt of the efflorescent kreatinin from kreatin is darker in 



