Changes in the Nervous System in a Case of Dourine, etc. 



Plate 4. — Sleeping Sickness. 



7. — Posterior spinal ganglion, case of chronic Sleeping Sickness, showing ■wide-spread 



interstitial chronic inflammation. Polychrome eosin stain. Section 10 p 

 thickness. Magnification X85. 



8. — Ditto. Magnification X480. Showing the proliferation of the endothelial cells 



of the capsule and lymphocyte interstitial infiltration. 



9. — Section of the spinal cord, chronic Sleeping Sickness, showing septal glia prolifera- 



tion, partly due no doubt to degenerative atrophy of the nerve-fibres. Weigert 

 stain. Sections 30 fi thickness. Magnification X80. 



10. — Section of a vessel with surrounding lymph space, chronic Sleeping Sickness. A 



meshwork of fibrils is seen, derived from the branching processes of the 

 neuroglial cells. The neuroglia nuclei are stained, the lymphocytes are 

 unstained. Magnification X 480. 



11. — Vertical section of a perivascular space in the brain of the monkey which died of 



chronic Sleeping Sickness. Material kindly given by Major Leishman. Stained 

 by polychrome eosin. Three large neuroglia cells, with branching processes, 

 are seen, and many others in parts. Entangled in the meshwork are numerous 

 lymphocytes. Magnification x 600. 



12. — Section of monkey's brain infected with T. Gambiense, showing glia cell prolifera- 



tion. Many of the glia cells can be seen with their processes extending on to 

 the wall of the vessels. There is a glia cell nuclear proliferation also. 

 Heidenhain, eosin stain. Magnification x 250. 



