1906.] Experimental Analysis of the Growth of Cancer. 211 



healthy layer on deep surface adjacent to muscles. Posterior tumour practi- 

 cally complete necrosis with thin healthy layer under skin. Skin slight 

 early ulceration. The posterior tumour penetrated abdominal wall, pressing 

 on and displacing kidney. 



Transplantation into 40 young normal mice, of which two died within 

 10 days. In the remainder 32 tumours developed as under : — 



No. of 

 mouse. 



Day of 

 growth. 



Weight of 

 mouse. 



Weight of 

 tumour. 



^fnl» Pfl .pvp ATYnpnTanpp 



Result of 

 transplanting. 







grammes. 



grammes. 







ucr C/CiiL. oi J. . 



1 



11 



10-7 



1 -45 





fid 



2 



12 



10 -3 



1-3 



Early diffuse necrosis ... 



fifi 

 uo 



51 U. 



3 



12 



9-7 



0-85 





1 9 



51 V. 



4 



14 



10 -o 



Too small 















to weigh. 









5 



17 



14 -8 



1 -82 



Diffuse marked necrosis 



13 



„ 51 W. 



6 



18 



9-8 



1 1 



Central necrosis. 







7 



19 



8 -9 



2 



No necrosis. 







8 



19 



17 -5 



1 -34 



Early diffuse necrosis . . . 



>> V 



45 



„ 51 Y. 



9 



19 



8 "45 



1 -4 



35 



51 Z. 



10 



19 



7-66 



1 -84 



>> >3 



21 



„ 51 iiA. 



11 



20 



11 9 



9 



Complete necrosis. 







12 



20 



13 -2 



0-3 



Central necrosis. 







13 



20 



9-1 



2-4 



Necrosis almost com- 



53 



51 iiB. 











plete, therefore diffi- 















culty in transplanting 







14 



20 



9-05 



0-95 



Marked necrosis. 







15 



20 



19 -65 



1 -05 



Marked diffuse necrosis 



22 



51 iiD. 



16 



21 



10 -7 



1 -1 



Complete necrosis ulce- 















rated. 







17 



21 



9-9 



0-7 



Diffuse necrosis. 







18 



21 



15 -05 



0-55 



Practically complete ne- 















crosis. 







19 



21 



8-2 



0-9 



Early very slight ne- 



28 



51 iiF. 











crosis 







20 



21 



11 35 



1 -15 



Early slight necrosis 



25 



51 iiG. 



21 



23 



10 3 



1 -3 



Marked necrosis. 







22 



25 



10 1 



0-5 



Diffuse necrosis. 







23 



25 



9 



1 -o 



Very slight early ne- 



7 



,, 51 iiJ. 



24 



25 



12 -8 



0-6 



8 



51 iil. 











crosis 







25 to 32. — Nine other tumours ceased growing after three weeks and were 

 ultimately completely absorbed. The mice were then re-inoculated. 



Transplantation 51, Series T. 



Parent tumour. Young white female of Transplantation 50, Series Z. 

 Tumour weighed l - 45 grammes, mouse alone weighed 10 - 7. Tumour situated 

 between scapulae, soft in consistence, very vascular, no haemorrhage, no 

 necrosis. 



