1906.] 



Chloroform in the Blood of Animals. 



435 



hb7 



& 



•a 



u I 



3 



IQ-30 



LighC ether 



I pjn. 



RespiraSr Gratings Respira.^ tracings 

 - — very similai ' 



D. 



Constructed from Experiment 8. Samples of arterial blood ( + ). 



just disappeared, when the animal was moderately deeply under, and when 

 respiration was stopping. The animal was then allowed partially to revive, 

 and a sample was taken when the reflexes were well marked. Chloroform 

 was now administered again, and samples were collected when the reflexes 

 had just disappeared, when the animal was deeply under, and when respiration 

 began to cease, the various points at which the blood was taken being selected 

 so as to correspond as far as we could judge with those in the first part of 

 the experiment. 



The results of the experiment are given in Table VIII and Curve D. It 

 will be noticed that the two portions of the curve correspond in form, but 

 the second part is slightly shifted in an upward direction. 



Experiment 9. — The object of this experiment was to test the effect on the 

 amounts of chloroform necessary to produce various anaesthetic phenomena 

 of taking away a large proportion of the animal's blood, which is undoubtedly 

 the vehicle through which chloroform is enabled to produce its effects on the 

 animal. For this purpose a female cat, weighing 3"3 kilogrammes, was 

 selected, and the chloroform was administered by means of a Woulff s bottle, 

 in which the height of the air inlet tube above the chloroform could be varied 

 readily. After the control sample of blood had been withdrawn, the animal 



