1906.] 



Chloroform in the Blood of Animals. 



443 



12 



T3 



8 11 



































t 





































































f 



































\ — 























































f 













t 1 

















































































































































































































bo 



I 

 t- 



<U 



I 



°o 



3 



5 



1 



Ether 



2% 3% 4-5% 4-5% 

 CHClj CHd 3 CHC1 5 CHC1 5 



died. 



A 



Reflexes 

 just gone 



G. 



A 



Reflexes 

 just appeared 



Constructed from Experiment 11. Samples of arterial blood ( + ). 



General Conclusions. 



No previous observations on cats are available for reference ; all the 

 observers whose work has been considered in the earlier part of this paper 

 carried out their investigations exclusively on dogs. 



It is difficult in any case to ascertain the exact moment at which an animal 

 is really anaesthetised. In our experiments we have taken the moment of 

 the disappearance of both conjunctival reflexes as a fixed point, though the 

 determination of this presents some difficulties, since the reflex may disappear 

 from one eye a minute earlier than in the other. The cessation of the tail- 

 reflexes may sometimes precede, sometimes succeed that of the conjunctiva. 

 The times when samples of blood were taken in our experiments at this stage of 

 anaesthesia slightly differ ; for example, blood was withdrawn sometimes when 

 the conjunctival reflexes definitely disappeared, sometimes when they 

 definitely reappeared, sometimes at a point when they had almost vanished 

 or had returned in one eye. 



Combining the results of the experiments described, which form only a 



