450 Messrs. G. A. Buckmaster and J. A. Gardner. [July 11, 



Table XVI.— Dog. Weight, 23 lbs. 



Time. 



Anaesthetic. 



Weight 

 of blood 

 + 0-25 

 c.c. 

 oxalate 

 of soda. 



Weight 

 of 

 AgCl. 



Total 

 percent- 

 age of 

 chlorine. 



Differer 



As 

 chlorine. 



ice from c 



As 

 CHC1 3 . 



ontrol — 



As 

 vapour 

 ofCHCL. 

 at 0° C. 



and 

 760 mm. 



Weight 

 of cor- 

 puscles. 



Weight 



of 

 AgCl. 





12 noon 



P.M. 



12.55 

 1.0 



1.4 

 1.15 

 1.23 

 1.32 



Ether began. 



Very light ether 



Chloroform on, 2 per 

 cent. 



» >> 

 3 per cent. on. 

 4'5 per cent. on. 



4 -8812 



5 -0918 



# 



-0544 

 '0601 

 # 



-27473 

 -29096 



# 



-0162 

 # 



-0182 

 # 



3 -42 

 # 



2 -3997 

 2 -4859 

 2-4743 



-0194 

 -0224 

 -0267 



* These values could not be calculated, owing to 

 Percentage of chloroform taken by corpuscles 



Table XVII.— Cat. 













Difference from control — 















Weight 

 of blood 

 + 0-5 c.c. 

 oxalate 

 of soda. 





Total 

 per- 

 centage 

 of 



chlorine. 













Per- 





Time. 



Anaesthetic. 



Weight 

 of 

 AgCl. 



As 

 chlorine. 



As 

 CHC1 3 . 



As 

 vapour 

 ofCHCLj 

 at 0° C. 



and 

 760 mm. 



Weight 

 of cor- 

 puscles. 



Weight 



of 

 AgCl. 



centage 



of 

 chlorine 

 in cor- 

 puscles. 





P.M. 



3.0 



3.41 



3.42 



3.47 



4.30 



Ether began. 



Ether on 



Ether off. 

 CHC1 3 on, 2 per 

 cent. 

 >> )> 



10 "1997 

 10 -0375 



-1340 

 -1400 



-32385 

 -34382 



-01997 



-0224 



4-2 



3 -9132 

 3 -8050 



"0386 

 -0460 



-2431 

 0-298 





Percentage of total chlorine 



Conclusions. — It would appear from these experiments that in cats the 

 chloroform associates itself primarily with the red corpuscles, and never 

 gets into the plasma unless the anaesthesia is pushed to an extreme point and 

 the anaesthetic is rapidly administered. This conclusion also applies to dogs, 

 but in this case the chloroform appears to enter the plasma somewhat more 

 readily on pushing the anaesthetic. This conclusion is also in agreement with 

 the results of Nicloux. 



