210 On Tubercular Infection in a Patient's Blood, etc. 



Appendix. 



A further Series of Observations showing that Phagocytosis is obtained with 

 the Heated Serum of Patients who are the subjects of a Systemic as 

 distinguished from a strictly Localised Tubercular Infection, or who, 

 being the subjects of a strictly Localised Tubercular Infection, have been 

 subjected to Inoculations with Tubercle Vaccine. The serum was in each 

 case heated to 60° C.for 10 minutes. 



Table supplementary to Table II. — Showing that the Normal Serum, after it 

 has been exposed to a Temperature of 60° C. for 10 minutes, no longer 

 incites Phagocytosis. 



Serial 

 number 

 of obser- 

 vation. 



Nature of infection. 



TJnheated serum. 



Phagocytic 



count. 

 (Number of 

 bacteria 

 ingested divided 

 by number of 

 leucocytes 

 examined.) 



Opsonic 

 index 

 (determined 

 by compari- 

 son of 

 phagocytic 



count 

 with that 

 obtained 

 with pooled 



blood of 

 healthy men) 



Heated serum. 



Phagocytic 



count. 

 (Number of 

 bacteria 

 ingested divided 

 by number of 

 leucocytes 

 examined.) 



Opsonic 

 index 

 (determined 

 by compari- 

 son of 

 phagocytic 



count 

 with that 

 obtained 

 with pooled 

 unheated 

 blood of 

 normal men) 



9 

 10 



11 

 12 



Fibroid phthisis, tu- 

 bercle bacilli in 

 sputum 



Early phthisis, tu- 

 bercle bacilli in 

 sputum 



Acute phthisis, tu- 

 bercle bacilli in 

 sputum 



Acute phthisis 



Fibroid phthisis (?) ... 



Phthisis, tubercle 

 bacilli in sputum 



Mitral stenosis 



Early phthisis , 



Phthisis 



Lupus under treat- 

 ment by inoculation 

 of tubercle vaccine 



Lupus under treat- 

 ment by inoculation 

 of tubercle vaccine 



Tubercular ulcer of 

 leg under treatment 

 by inoculation of 

 tubercle vaccine 



(100/30) = 3-3 



(132/30) = 4-4 



(130/30) = 4-3 



(127/40) = 3-2 

 (182/30) = 6-0 

 (117/30) = 3-9 



(106/30) 

 (161/30) 

 (257/40) 

 (131/36) 



3 5 



5- 4 



6- 4 

 3-3 



(73/30) = 2-4 

 (63/30) = 2-1 



1 -o 



1-3 



1 3 



1-0 

 1-8 

 1-1 



1 -o 



1-6 

 1-3 

 1-6 



1 -2 



1-2 



(142/37) = 4-0 



(122/47) = 2-6 



(96/40) = 2-4 



(45/34) = 1-3 

 (51/43) =1-2 

 (65/30) = 2-2 



(19/31) 

 (54/27) 

 (51/40) 

 (74/40) 



0- 6 

 2-0 



1- 3 

 1-8 



(31/30) =1-0 

 (60/30) = 2-0 



1-2 



0-77 



0-74 



0-4 

 0*3 

 0-62 



0-17 

 0-6 

 0-27 

 0-8 



0- 5 



1- 1 



The first eight of the observations here in question were made upon bloods collected for us in 

 the Victoria Park Hospital by our fellow worker, Dr. Gr. W. Eoss. The clinical diagnosis which 

 had been arrived at was not made known to us till afterwards, when the particulars set forth in 

 Column 2 were filled in by Dr. Eoss. 



