1906.] 



Specificity and Action in Vitro of Gastrotoxin. 441 



Upper Stomach. — From a guinea-pig which was injected with gastrotoxic 

 serum previously treated with blood corpuscles. Necrosis of the mucous 

 membrane has resulted, because red blood corpuscles will not combine with 

 the gastrotoxin. 



Lower Stomach. — From the control animal, which was injected with the same 

 dose of untreated gastrotoxic serum, necrosis of the mucous membrane has 

 therefore resulted. 



Fig. 6. — Illustrates the fact that rabbit's stomach cells will not remove the gastrotoxin 

 from guinea-pig- rabbit gastrotoxic serum. 

 Upper Stomach. — From the control animal, which was injected with untreated 



serum, and therefore shows extensive necrosis and haemorrhage. 

 Lower Stomach. — From a guinea-pig which was injected with gastrotoxic 

 serum, previously treated with rabbit's stomach cells. The cells have failed fc 

 to remove the gastrotoxin from the solution, and lesions similar to those of 

 the control animal have resulted. 



Fig. 7. — Illustrates the hsemolytic lesions which are produced in a guinea-pig's stomach 

 by the injection of a guinea-pig-rabbit entrotoxic serum. As seen here, the 

 lesions are indistinguishable from those produced by gastrotoxic serum. 



Fig. 8. —Illustrates the fact that guinea-pig's stomach cells will not remove the 

 haemolysin from guinea-pig-rabbit haemolytic serum (obtained by injecting 

 red blood corpuscles). Haemolytic patches are seen in the stomach, which is 

 that of a guinea-pig. The animal was injected with guinea-pig-rabbit 

 haemolytic serum, prepared by injecting the red blood corpuscles of the 

 guinea-pig into the rabbit. Before its injection the serum was mixed with 

 stomach cells for one hour. The stomach cells have failed to remove the 

 haemolysin from the serum. 



