16 Messrs. Ellis and Gardner. Origin and [Sept. 3* 



118'1 grm. of dry faeces. On extraction, this yielded 4"492 grm. of 

 unsaponifiable matter, from which 3"3306 grm. of coprosterol were obtained. 

 The balance sheet works out as follows : — 



Total cholesterol (free and com- Total coprosterol excreted 3"3306 



bined) ingested with food ... 3'6183 Output per diem 0'4758 



Intake per diem 0"51fi9 



Difference, - 0411 of cholesterol per diem absorbed. 



Series III. — Then followed seven days on Diet II. During this period the 

 patient was sickening for an attack of influenza. His weight varied as 

 follows : 75, 74-6, 74-2, 74-3, 74*3, 74-2— average 74'4 kgrm. The average 

 loss in weight from the average of the previous period was thus 900 grm., or 

 an actual loss during the week of 800 grm. Three stools were passed, 

 containing 118 grm. of solid matter. This yielded 3"9605 grm. unsaponifiable 

 matter, from which were obtained 2 - 6505 grm. of coprosterol. The balance 

 sheet works out as follows : — 



Total cholesterol ingested 1"587 Total coprosterol excreted 2 - 6505 



Intake per diem 0'2267 Output per diem 0-3786 



Excess of cholesterol excreted T0635 



„ „ per diem 0'1519 



If we reckon the loss in weight as due to fat and protein tissues the loss of 

 cholesterol in this way would be from 0'45 to - 8 grm., which would largely 

 account for the excess excreted over intake. 



Series IV. — During the next five days the patient suffered from influenza. 

 Two meals of Diet II were taken and 35 grm. of dry faeces were obtained. 

 The weights of the patient were as follows : — 74*2, 72"6, 73 - 2, average 73 - 3. 

 The faeces excreted during the first four days yielded l - 7638 grm. of 

 unsaponifiable matter, from which T3109 grm. of coprosterol was obtained. 



Total cholesterol ingested dur- Total coprosterol excreted 1 - 3109 



ing period 0'4534 



Excess of cholesterol excreted 0'8575 



„ „ per diem 0'2144 



The patient lost during illness 1*5 kgrm., so that about 1 grm. of 

 cholesterol might be accounted for in this manner, and the excess of output 

 over intake explained. 



Series V. — During recovery from illness the patient was fed for six days on 

 an ordinary mixed diet, after which the experiment was continued. He was 

 fed for 33 days on Diet II, with addition of various salts, for one day on 

 100 grm. egg-white and 250 grm. boiled-out meat, for another day on 

 250 grm. of boiled-out meat, and for three days on a total of 400 grm. 

 egg-white + 1250 grm. herring-roe. 



