180 



Messrs. E. C. Hort and W. J. Penfold. [Feb. If, 



In the experiments illustrated by the curves A the water injected was 

 ordinary distilled water and contained 40 organisms per c.c. In the case 

 of the experiments illustrated by curves B, the saline was made with 

 freshly distilled water and at once injected. The results here recorded 

 occurred in all essentials in all of the 27 experiments made. Numerous 

 papers dealing with salt fever have appeared (7-14) in which various 

 theories based on the view that salt was the pyrogenetic agezit have been 

 advanced. The evidence in support of these views no longer holds good. 



Carbohydrate Fever (Charts 6, 7, 8). 



Charts 6 and 7 show that the injection of glucose and saccharose produced 

 no fever when the solutions injected were made in pure water. 



Chart 8 shows temperatures obtained in two experiments made with lactose 

 from different sources. The solutions were made in pure water. The upper 

 curve shows the result with a sample of commercial lactose. The lower 

 curve shows the result with lactose made from a catheter sample of cow's 



01 23 4 55739 



A. Rabbit, 1545 grin., injected intravenously with 8 c.c. 5-per-cent. glucose in water 



containing F.P.B. Injection ratio, 1/193. 



B. Rabbit, 1718 grm., injected intravenously with 8 — 9 c.c. 5-per-cent. glucose in freshly 



distilled water. Injection ratio, 1/193. 



(Interval between observations, 30 minutes.) 



