182 Messrs. E. C. Hort and W. J. Penfold. [Feb. 17, 



Tissue Fever (Charts 9, 10, 11). 

 Chart 9 shows that the presence of F.P.B. is also responsible for the fever 

 that follows the injection of blood laked with water, and that injection of 

 similar quantities of blood laked with pure water produces marked fall of 

 temperature. This fall, as will be seen, is due to the depressant effect of two 

 distinct factors, pure water and extract of red cells. 



O 12 3 4-56 



A. Rabbit, 2590 grm., injected intravenously with 4'6 c.c. rabbit blood in 15"3 c.c. water 



containing F.P.B. Injection ratios, 1/563 and 1/169. 



B. Babbit, 2197 grm., injected intravenously with rabbit blood in pure water. Injection 



ratios as in A (slightly less). 



(Interval between observations, 30 minutes.) 



Chart 10 shows the relative temperatures after injection of two animals 

 with extract of red blood cells taken from another animal of the same 

 species. The extract was made in the case of animal A by lysis of the 

 cells in water shown to contain F.P.B., the extract for animal B being 

 made in pure water. This chart destroys the value of the evidence of fever 



