The Measurement of Trypanosoma rhodesiense. 



223 



first hour was 108 per minute, while feeding with diabetic blood ; during the 

 second hour, after the addition of pancreatic extract to the same blood, the 

 heart beats rose to 144 per minute. 



We hope to continue these experiments, and especially to determine the 

 respiratory quotient in the normal and in the diabetic heart, and the 

 influence of pancreatic extract on the same. So far as our results go, they 

 seem to indicate that the pancreas normally produces a hormone which 

 circulates in the blood, and the presence of which is necessary in order that 

 the tissue cells may be able to assimilate and utilise the sugar of the blood. 

 In fact, they indicate that the second of the two explanations, which have 

 been mentioned above as having been proposed for the occurrence of 

 pancreatic diabetes, is essentially correct. 



EEFEEENCES. 



(1) Von Mering u. Minkowski, 'Arch. f. exp. Path. u. Pharm.,' 1889, vol. 26, p. 371. 



(2) Jerusalem and Starling, ' Jouni. of Physiology,' 1910, vol. 40, p. 279. 



(3) Chauveau and Kaufmann, ' Compt. Eend. Soc. de Biol.,' 1893. 



(4) Locke and Eosenheim, ' Journ. of Physiology,' 1907, vol. 36, p. 205. 



(5) Eohde, ' Zeitsch. f. physiol. Chemie, 1 1910, vol. 68, p. 181. 



The Measurement of Trypanosoma rhodesiense. 

 By J. W. W, Stephens, M.D. Cantab., D.P.H., and H. B. Fantham, 

 D.Sc. Lond., B.A. Cantab. 



(Communicated by Sir Ronald Eoss, K.C.B., F.R.S. Received March 28,— 

 Read May 2, 1912.) 



[Plate 3.] . ' 



Introduction. 



The following paper contains the results of a biometric study of Trypanosoma 

 rhodesiense (Stephens and Fantham). 



This trypanosome, which is dimorphic, was described by us in July, 1910. 

 It was considered to be a new species of trypanosome, producing Sleeping 

 Sickness in man, since it could be distinguished morphologically by the fact 

 that a certain percentage of short forms showed the nucleus either close to or 

 even posterior to the blepharoplast, a feature which has never been recorded, 

 for T. gambiense, either before or since. 



Otherwise, in external • morphology T. rhodesiense closely resembles 

 T. gambiense, for there are long, slender forms and short, stumpy forms, 

 together with intermediate forms. These flagellates were figured by us 



