328 



Dr. E. K. Martin. 



[Feb. 5, 



of the pupil and hyperemia of the iris. At the end of the series of exposures, 

 both iris and ciliary body were normal on microscopical examination, so that 

 to determine if a slight ciliary irritation persisted in the intervals between 

 successive exposures a more delicate test of such irritation had to be employed. 



For this purpose advantage was taken of an observation of Romer's (Ref. 15) 

 that the aqueous of animals which had been sensitised to the erythrocytes of 

 a foreign species had no power to hsemolyse the blood of that species. If, 

 however, when the anterior chamber had reformed, a second paracentesis was 

 done, the aqueous obtained was actively hemolytic. Similarly, if slight 

 iridocyclitis was induced the same result followed. 



Rabbits were rendered hemolytic by injection with washed cats' corpuscles 

 intraperitoneally in doses of 5, 10, 15. and 20 c.c. at intervals of four days. 

 Haemolysis is most active 8-10 days after the last injection. 



Romer's observations were first confirmed as follows : — 



First aqueous, 9 cases ~No haemolysis. 



Haemolysis following simple paracentesis : — 



Present 1, 4, 6, 7, 8 days later. 



Haemolysis following slight injury to iris by point of paracentesis needle : — 



8 weeks later Slight haemolysis. 



10 „ No 



Haemolysis following Exposure to Quartz Mercury-vapour lamp. 

 Left eye exposed. Right eye control. 



Exposure. 



Paracentesis. 



Haemolysis. 



L. 



E. 



i » „ 



1 „ „ 



3 „ „ 



3 ., „ 



3 ., „ 



3 „ „ 



6 tours later 

 5* „ 

 5 



At end of exposure 

 1 day later 

 3 days later 

 3 

 4 

 6 

 8 



Nil 



Faint, positive 

 Positive 



Nil. 



