J 912.] T. pecorum {Bruce) and T. uniforme (Bruce). 559 



It will thus be seen that no local epidemic of T. pecorum disease, such as 

 affected the transmission work of the 1908 — 1910 Commission, interfered with 

 the above experiments. 



The interesting result obtained in Experiment 688 proves tbat T. pecorum 

 can exist in antelope for at least 323 clays. During this time it apparently 

 exerts no harmful effect upon the host. The bushbuck, Experiment 55, is 

 to all appearances in excellent health, and has been growing rapidly throughout 

 the period covered by these experiments. 



An interesting point also is the rapid course of the disease in Calf 688, which 

 died in 51 days. Previous to the introduction of the trypanosome into the 

 bushbuck there were some signs that the organism was losing its influence, 

 possibly owing to continued maintenance in laboratory animals. Thus 

 •Calf 33, which was inoculated with the old laboratory strain of T. pecorum 

 from a monkey, first showed trypanosomes on May 13, 1910. The animal is 

 still alive and in good condition, and was showing T. pecorum in its blood on 

 August 29, 1910 ; since then the blood has not yet been examined. 

 Bushbuck 55 was inoculated from the same monkey as Calf 33. 



There is, of course, the possibility that the extraordinary course of the 

 disease in Calf 33 is due to some immunity peculiar to this individual. 

 Previously, all calves inoculated with this laboratory strain had died of an 

 acute disease. 



It will be noticed, however, that the long sojourn in the bushbuck did not 

 render the trypanosome more suited to development in G. palpalis, in contrast 

 to the behaviour of T. aamhiense under similar circumstances. 



Trypanosoma, uniforme. 



As has been pointed out elsewhere, this organism appears to be the most 

 common antelope trypanosome in the Mpumu neighbourhood. According to 

 Bruce and his collaborators, it causes a fatal disease in domestic ruminants, 

 the average duration of the disease in three laboratory -infected goats being 

 29 days. 



My experience of this trypanosome, extending over some 20 months, has 

 not confirmed this opinion. T. uniforme has not proved in any way a fatal 

 trypanosome during that time. In only one case has an animal died of an 

 unecpiivocal T. uniforme infection, this being apparently the case with 

 Calf 481, although for months before death no trypanosomes were visible 

 in the peripheral blood. 



A characteristic feature of T. uniforme, which is especially marked in 

 goats, is the manner in which, after a few weeks, it totally disappears from 



