1909.] Experimental Treatment of Trypanosomiasis. 365 



Dilutions of atoxyl. 



Time. 



Dilutions of lithium antimonyl tartrate. 



1—500. 



1—1000. 



1—5000. 



1—500. 



1—5000. 



1—10,000. 



Trypanosom.es, 

 all active 

 Active but 

 affected 



Less active 



Practically 

 motionless 



Active 

 >> 



Sluggish, but 

 still many 



active 

 Nearly all 



motionless ; 



1 or 2 active 

 forms seen 



Active 

 jj 



u 



Many 

 moving 

 still 



1 min. 

 5 mins. 



15 „ 



2 hrs. 



Trypanosomes, 

 all motionless 

 Motionless : 

 commencing 

 disintegration 

 Only debris 

 seen 



»> 



All markedly 

 affected 

 Motionless 



jj 



Disintegrated 



All fairly active. 

 Less active. 



Some still moving ; 

 tendency to clump. 



Motionless ; some 

 disintegration. 



Concentrated decoction of quassia in 089 per cent, salt solution mixed 

 with Surra rat's blood in equal parts. 



Dilutions. 



Time. 



Control. 



1—500. 



1—1000. 



1—5000. 



1—10,000. 



Tery active 



JJ 



Less active 



Very active 



3) 

 JJ 



Less active 



Very active 

 Less active 



Very active 

 )» 



Less active 



1 min. 

 10 mins. 

 30 „ 



1 hour 



2 hours 



Very active. 

 Less active. 



The conditions of the dilutions and the control were precisely similar at 

 the end of two hours. There was no swelling nor clumping. 



Dilutions of arsenophenylglycin in 089 per cent, salt solution mixed with 

 Surra rat's blood in equal parts. 



Dilutions. 



Time. 



Control. 



1—100. 



1—500. 



1—1000. 



1—5000. 



1—10,000. 



Very active 

 Irritated : move- 

 ments rapid and 

 convulsive 

 Nearly motion- 

 less 

 Motionless 



Very active 

 Activity 

 increased 



Sluggish 



Very active 

 >> 



Very active 

 » 



Very active 

 » 



1 min. 

 10 mins. 



30 „ 

 1 hour 



Very active. 



jj 

 jj 



