554 



Dr. A. D. Waller. Comparative Power of [June 24, 



This relation is not confined to this particular strength. In an experiment 

 with 2 m. alcohol and 0'02 m. chloroform, the two reagents produced 

 substantially equal effects (October 6). 



II. Alcohol v. Ether. 



Similar considerations apply to the estimation of the relative physiological 

 efficiency of alcohol and ether. 



As compared with a molecular solution of ethyl alcohol it was found — 



That a 01 mol. solution of ether was too weak, 

 „ - 2 „ „ too strong, 



„ 015 „ slightly too strong, 



and that the closest approximation to equality of effects was obtained 

 with 013 and 012 mol. solutions, from which it is concluded that 

 molecule for molecule ether is between seven and eight times as powerful 

 as alcohol. 



III. Chloroform v. Ether: 



Similar considerations apply to the estimation of the relative physiological 

 efficiency of chloroform and ether. 



We commenced by comparing the effects of a 1-per-cent. (by volume) 

 solution of ether and a l-per-1000 solution of chloroform, these two strengths 

 being respectively equal to 01 m. and 0"012 m. The ether solution proved to 

 be considerably the weaker of the two. 



For the next trial we took double the strength of ether, viz., 2 per 100 or 

 0*2 m., and found that at this strength the ether solution was considerably 

 stronger than a chloroform solution of - 8 per 1000 (= 0*01 m.). In a 

 further comparison between ether, - 15 m., and chloroform, - 01 m., the 

 former was still considerably the stronger, and from further trial of 013 m. 

 and of 0-1 2 m. ether we finally determined as nearest to physiological 

 equivalence : 



0-01 chloroform = 012 ether. 



