1911.] Immunisation by Means of Bacterial Endotoxins. 51 



Series II. — Inoculated with 01 mgrm. of Typhoid Endotoxin on May 14, 

 1909. 



Table II. — Inoculated with Living Culture on June 18, July 7, July 21, and 





July 2 



}, 1909. 





Eeference No. of 

 guinea-pig. 



Date of 

 inoculation. 



Amount of 

 culture. 



Eesult. 



27 

 10 

 12 

 17 

 22 



June 18 

 July 7 



5 M.L.D.'s 



2 „ 

 2 „ 

 5 „ 

 5 „ 



Lived. 



30 

 32 

 34 

 20 



July 21 



5 



8 „ 

 8 ., 





1 



8 

 14 

 31 

 Control 



July 28 



8 „ 

 8 „ 

 8 „ 

 8 „ 

 8 „ 

 4 



+ Dead, July 22. 

 Lived. 



+ Dead, July 29. 



The controls to the animals inoculated on June 18, July 7, and July 21 

 were the same as those in Table I. 



Series III. — Inoculated with 0'01 mgrm. of Typhoid Endotoxin on May 26, 

 1909. 



Table III. — Inoculated with Living Culture on June 18, July 7, July 21, and 

 July 28, 1909. 



Eeference No. 

 of guinea-pig. 



Date of 

 inoculation. 



Amount of 



Eesult. 



61 

 67 

 53 

 46 

 58 

 62 

 68 

 44 

 50 

 55 

 63 

 64 

 40 

 52 



June 18 

 July 7 



July 2L 

 July 28 



5 M.L.D.'s 



2 



2 



5 



8 



8 

 8 

 8 

 8 

 8 

 8 



+ Dead, July 22. 

 + .> i, 



+ Dead, July 22. 

 + „ „ 

 + „ July 29. 

 Lived. 



The controls to the animals inoculated on June 18, July 7, and July 21 

 •were the same as those in Table I, and on July 28 as in Table II. 



