1911.] 



by means of Bhipicephalus appendiculatus. 



115 



rather soft. The kidneys were rather pale ; the boundary zone of the right 

 kidney was slightly hyperaemic ; the capsule was easily detachable. The 

 bladder contained clear, yellow urine. 



Microscopical Examination. — Koch's granules were found frequently in the 

 lymphatic glands and spleen. 



Diagnosis. — East Coast fever. 



The infestation of two calves with adult brown ticks collected 

 as nymphse in Uganda from a calf suffering from acute Amakebe, was 

 succeeded in both instances by a fatal disease, which could be diagnosed as 

 East Coast fever from the appearance of the so-called Koch's blue bodies 

 or plasma granules, which represent, according to Gonder, the agametes, 

 agamonts, and gamonts in the life cycle of Theileria parva. The post-mortem 

 examination corresponds with Amakebe of Uganda, and with what is known 

 as East Coast fever. The fact that the blood of the first calf did not show 

 blood parasites is nothing unusual in Amakebe. The agamonts were there, 

 no gamonts had yet developed, accordingly no gametes of Theileria parva 

 could be found. This calf apparently died at the beginning of the disease, 

 the animal being weakened by the preceding anaplasma inoculation. The 

 second calf represented in every respect a typical case of East Coast fever. 



Conclusion. 



Amakebe of Uganda is identical with East Coast fever of South Africa, 

 and is transmitted by the tick Rhipicephalus appendiculatus. This conclusion 

 corroborates that obtained by the Eoyal Society Sleeping Sickness Com- 

 mission of 1909. 



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