324 Messrs. Hayden and Morgan. Influence of the [Aug. 24, 



In this last experiment, the appearance as regards the degree of opacity, 

 and so the quantity of detritus, in the emulsion A, was such as to lead us to 

 believe that, had a serum with a low index been tested with it, a low index 

 would have been obtained. The emulsion B was far more opaque than A, 

 and so a further experiment was performed. Three emulsions were prepared, 

 using such quantities of dried tubercle bacillus as to obtain varying amounts 

 of detritus : (A) containing a small quantity ; (B) a larger quantity ; (C) a 

 very large quantity. 



Indices were estimated with these three emulsions, using two normal sera 

 and two patients' sera, one whose index was expected to be high, and another 

 whose index was usually low. The following were the results : — 





(A) 



(B) 



(C) 



Phagocytic 

 count. 





Phagocytic 

 count. 



Index. 



Phagocytic 

 count. 



Index. 





}:JS}l'87 1-00 

 1-66 1 1 -21 

 0-92 -67 



1 



is}*- 



2-19 

 1 -12 



1 -oo 



1 -19 

 0-61 



1-841 7 

 1-58 J 1 n 

 3 "44 



1 -oo 



1 -oo 



2-01 

 0-58 



And a repetition of this experiment, using two different emulsions — 

 (A) containing a moderate quantity of detritus, and (B) containing a large 

 quantity — and using the sera of three other patients, gave the following 

 results : — 





(A) 



CB) 





Phagocytic 







Phagocytic count. 



Index. 



Normal i 



1-381 



► 1-41 



1-00 





1-00 





1 -44 



Patient i 



1 -55 

 1 -73 





1-10 

 1 -22 



1- 93 



2- 53 



1 -41 

 1-85 





0-48 





0-33 



0-48 



0-34 













Thus, when little or no detritus was contained in the emulsion, the 

 indices were in all cases within normal limits. When detritus was present 

 in moderate quantities, differences emerged between bloods of normal and 

 subnormal opsonic power, but supernormal bloods were not differentiated 

 from normal bloods. When emulsions which contained larger quantities of 

 detritus were employed, both subnormal and supernormal bloods were clearly 

 differentiated from normal bloods. 



