360 Messrs. G. A. Buckmaster and J. A. Gardner. [Aug. 19, 



Table VII. 





Frequency. 



Average depth. 





9th min. 



20 



27 -66 



553 



The respiration lessened steadily after — 









14th min. 



33 



40-4 



1333 



17th „ 



38 



42 o 



1615 



18th „ 



37 



42 -5 



1572 



20th „ 



Reflexes observed and voluntary movements. 



Example II. — The animal from which the tracing of fig. 4 was obtained 

 ceased to breathe during the first minute of anaesthesia, and the chloroform 

 was stopped. Asphyxial gasps then set in, which gradually passed into 

 normal respiration. During the 10th minute the respiration was deep, 

 slow, and regular, and at the end of the 12th minute the reflexes re-appeared, 

 and also voluntary movements. The animal was now chloroformed a second 

 time for 8 minutes with 3 per cent, chloroform. There was no evidence of 

 any danger-point. Chloroform was stopped, and the animal allowed to again 

 recover to the same state as above. It was re-chloroformed for a third time 

 with 3 - 2 per cent, chloroform, and the effect of the drug was still less marked. 

 The first few minutes of the tracings in each case are given below (figs. 7 

 and 8) and the comparative figures of all three chloroformings in Table VIII. 



Fm. 7. 



Depth of respiratioD, 1 division = 21-28 c.c. ; time intervals, 30 sees. ; |, 3 per cent, 

 chloroform on. 



