364 Messrs. G. A. Buckmaster and J. A. Gardner. [Aug. 19, 



certainly have produced death within the first few minutes. This initial 

 Slowing was followed by increase in rate and decrease in depth. This is 

 a typical result and well illustrated in the tracing, fig. 10. 

 The data of this experiment are given in Table IX. 



Table IX. 



Intervals of time. 



Anaesthetic. 



Frequency. 



Amplitude, 

 in c.c. 



Ventilation. 



1 min. befoi 

 0-5 n 

 0-5 

 0-5 

 0-5 

 3rd 

 4th 

 5th 



e 0HC1, 



CHC1 3 2 -5 per cent, on 



Reduced percentage of 

 CHCI3 

 1 -3 CHC1 3 



1 -o „ 

 1 -o „ 

 1 -o „ 



1 '0 „ 

 CHCI3 off for 8 mins. 

 Reflexes and voluntary 



53 

 24 

 22 

 24 

 25 

 55 

 60 

 64 



48 

 27 

 45 

 34 

 32 

 29 

 27 

 24 



73 

 11 

 33 

 89 

 00 

 34 

 11 



2705 



1J00} 2131 



So } 1637 

 1614 

 1628 

 1536 



6th 

 7th 

 8th 

 9th 

 10th 





62 

 54 

 52 

 50 

 49 



23 

 24 

 29 

 33 

 39 



11 



39 

 11 



1433 

 1344 

 1514 

 1666 

 1905 



1 



05 

 0-5 

 0-5 

 0-5 

 0-5 

 0-5 



1 



:, . 



movements. 

 No CHC1 S 

 5 per cent. CHC1 :1 



35 

 11 

 9 

 10 

 14 

 18 

 25 

 6L 

 VI 

 70 

 70 

 64 

 55 



Ceased to 

 breathe 

 Asphyxial 

 convulsions 



46 

 36 

 33 

 34 

 28 

 22 

 19 

 18 

 16 

 15 

 15 

 14 

 13 



89 

 98 

 11 

 89 

 22 

 67 

 33 

 23 

 00 

 71 

 55 

 78 

 87 



1642 



i }705 



395} 744 



408 1-891 



483/ Syl 

 11L1 

 1137 

 1100 

 1089 



946 



749 



: Example IV. — In this experiment the animal was anaesthetised with 

 nitrous oxide ; the breathing after recovery was regular. 



It was then anaesthetised with 2 per cent, of chloroform for three minutes, 

 with slight evidence of a danger-point during the first minute, but the effect 

 was not very marked. The measurements are given in Table X. 



