512 Changes in Teeth of Guinea-pig, produced by Scorbutic Diet. 



S. S. Z. is responsible for the biochemical part of the investigation ; 

 r. M. W. for the histological work. 



REFEEENCES. 



Harden and Zilva (1919), ' J. Bact. Path.' (In the press.) 



Harden and Zilva (1918), 'Bioch. J.,' vol. 12, p. 259. 



Harden, Zilva, and Still (1919), 'Lancet,' January 4, p. 17. 



Hart and Lessing (1918), ' Der Skorbut der kleinen Kinder.' 



Hess (1917), 'J. Amer. Med. Assoc' January 27, p. 235. 



Hoist und Frolich (1912), ' Zeitsch. Hyg.,' vol. 72, p. 1. 



Talbot, Dodd, Peterson (1913), ' Boston Med. Surg. J.,' vol. 169, p. 232. 



DESCRIPTION OF PLATE. 



Fig. 1. — Longitudinal section through normal guinea-pig tooth. The pulp is mz situ. 



Prepared by decalcification. Stained with Ehrlich's acid haematoxylin. 

 Magnified 40 times. D, dentine ; B, blood-vessels ; O, odontoblasts ; 

 E, enamel ; B.L., basal layer of Weil. 



Fig. 2.- — Same as preceding figure. Magnified 200 times. 0, odontoblasts ; P, pulp 

 tissue ; B, blood-vessels. 



Fig. 3. — A transverse section of a guinea-pig tooth kept on a scorbutic diet for about 

 15 days. D, dentine ; E, enamel ; P, dead pulp, showing complete degenera- 

 tion of the pulp. Magnified 40 times, stained as in preceding figure. 



Fig. 4. — Same as fig. 3. Magnified 200 times. Prepared and stained as in preceding 

 figure. D, dentine ; D.O., degenerate odontoblasts ; P, dead pulp tissue 

 proper. 



Fig. 5. — Longitudinal section through piece of tooth of guinea-pig No. 273, broken oflF 

 29.6.18. P, pulp ; D, dentine. Stained and prepared as in preceding figures. 

 Magnified 40 times. 



