Antiseptic Action and Chemical Constitution. 365 



[90.] 2.Benzylamino-7.amino-3.6.dirnethyl;phenazine methochloride. — The 

 compound was prepared by heating together on the water-bath p-ditnethyl- 

 arnino o-toluidine dissolved in alcohol with nitroso benzyl o-toluidine hydro- 

 chloride and hydrochloric acid as describecTln the preparation of the methyl- 

 amino compound (p. 361). The colour developed passing from yellowish red 

 to red, with a faintly blue tint. On concentration and cooling the colouring 

 matter separated and was filtered and washed with ether. It has probably 

 the following formula : — 



N 



ch/VVNch, 



CeHs-CHa-NH^'^/'^HX, HC1. 



CH, CI 



The zinc salt is obtained by precipitating the methochloride in solution 

 with zinc chloride. 



[91.] 7.Am.ino-Q.methyl-2.dimethylamino-napthophenazine hydrochloride. — 

 The substance was prepared as follows : 2 - 3 grms. of nitroso dimethyl 

 a-naphthylamine hydrochloride were dissolved in 20 e.c. of hot glacial acetic 

 acid, and to the solution was added a solution of 1*2 grms. of //i-toluylene 

 diamine in 20 c.c. of 50 per cent, acetic acid. 1 c.c. of cone, hydrochloric 

 acid was then added and the mixture heated on the water-bath for 4 hours. 

 A magenta colour developed rapidly and lost its bluish tint on continued 

 heating, becoming gradually more crimson. It was finally boiled, diluted 

 with 100 c.c. of water and the hydrochloride precipitated with brine. For 

 purification it was redissolved in water and reprecipitated with brine. It 

 has the following formula : — 



[92.] 7.Amino-6.viethyl-2.dimethylaviinenapthophenazine methochloride. — 

 The process was carried out as above, but instead of ?/i-toluylene diamine 

 the p-dimethylamino o-toluidine was used. 24 grms. of nitroso dimethyl 

 a-naphthylamine hydrochloride were dissolved in 20 c.c. glacial acetic acid 

 and added to 1'5 grms. of dimethylamino-toluidine in 20 c.c. 50 per cent, 

 acetic acid, and 1 c.c. of cone, hydrochloric acid. The bright crimson colour 

 develops rapidly, and after 3 hours' heating on the water-bath was separated 



