42 Sir D. Bruce and others. Trypanosorne 



Table V — continued. 



Date. 



No. of 

 expt. 



Source of virus. 



Period of 

 incubation, 

 in days. 



Duration 



of disease, 

 in days.* 



Remarks. 









Rats. 







1912. 



Nov. 27... 



1660 



From Dog 1599 



5 



38 



Died of Strain V. 



97 

 „ 61... 



lUOl 





O 



OU 



„ 27... 



1662 



1599 



8 



39 



» >j 



1913. 

 Jan. 8... 



„ 28... 



1744 

 1817 



From G-uinea-pig 1658 

 From Monkey 1733 ... 



6 

 2 



20 



>> » 



.Killed January 22. 

 From Transmission Experi- 

 ment 1723. Died of Strain Y. 









5-2 



31 -8 





* Duration includes the days of incubation ; it dates from day of infection. 



Disease set tip in Various Animals by the Trypanosorne causing Disease in 

 Man in Nyasalancl. — I. The Human Strain. 



Ox. — This trypanosorne is not as deadly to oxen as Trypanosoma pecorum ; 

 13 experiments in all were made on cattle with the Human strain. Only one 

 of these died, after an illness lasting 134 days. Four took the disease and 

 recovered, while the remaining eight showed themselves refractory to the 

 injection of blood containing the parasites. One of the recovered animals has 

 been kept under observation for 325 days, and its blood was inoculated into 

 a rat without result. At the present time these so-called recovered animals 

 appear sleek and fat and look healthy, presenting a contrast to the chronic 

 T. pecorum infected cattle, which still remain in poor condition. The animal 

 which died was much emaciated, anaemic, and had marked gelatinous infiltra- 

 tion of the connective tissue at the base of the heart and large vessels. The 

 trypanosomes were never numerous in its blood, and in fact only showed six 

 times in the four and a-half months of its illness at the bi-weekly blood 

 examination. 



Goat. — This is a fatal disease in goats; 22 were used for experimental 

 purposes, and not one of them recovered. The duration of the disease, on an 

 average, was 41'8 clays (19 to 72). One of these animals showed swelling of 

 the face, but none developed opacity of the cornea. 



Sheep. — This trypanosorne seems as fatal to sheep as goats, killing seven, on 

 an average, in 41'1 days (16 to 87). Among these seven, oedema of the face 

 was noted as a prominent symptom in three. No opacity of cornea developed 

 in any of them. 



