514 



Sir D. Bruce and others. Description of a 



other is still alive at the end of a year. This animal has evidently recovered, 

 as it appears sleek and healthy. The action of the Zululand strain is 

 therefore the same as that of the trypanosome causing disease in man in 

 Nyasaland : neither of them show any marked power of producing serious 

 disease in cattle. 



Goat. — Seven goats were inoculated with this strain. Four died, on an 

 average, in 77"2 days (45 to 116). The remaining three proved refractory. No 

 oedema of face or corneal opacity was noted in any of the goats. The 

 Zululand strain seems to have less action on goats than the Nyasaland 

 trypanosome, but the number of experiments is small. In the latter the 

 duration of the disease was 41"8 days (19 to 72). 



Sheep. — No experiments were made with these animals in Nyasaland as it 

 was found impossible to procure them from the natives. 



Monkey. — Eight monkeys died, on an average, in 29*2 days (8 to 65). The 

 trypanosomes were always present in the blood, sometimes in enormous 

 numbers. In no case was oedema of the face or corneal opacity noted. After 

 death, enlargement of the spleen and liver, gelatinous infiltration at the base 

 of the heart, and haemorrhages in the epicardium were found. 



Dog. — Seventeen dogs were inoculated. All died, on an average, in 

 18"5 days (12 to 26). In eight dogs blindness caused by opacity of the 

 cornea was a prominent symptom, and in two swellings of the limbs were 

 observed. 



Babbit. — As only two rabbits were available at Kasu, six experiments 

 reported by Mr. Shilston are added. Eight rabbits died, on an average, in 

 32*7 days (27 to 39). The course of the disease in the Kasu rabbits was the 

 same as that described in a former paper* as being typical of Nagana. 



Guinea-pig. — This animal is less affected by the disease than the rabbit. 

 Ten were used ; all took the disease and died, but four required to be 

 inoculated more than once. They died, on an average, in 43 - 7 days 

 (15 to 89). No prominent symptoms, such as are seen in the rabbit, occur 

 in the guinea-pig. 



Bat. — Twenty-three were inoculated and died, on an average, in 27 days 

 (10 to 58), with their blood swarming with trypanosomes and their spleens 

 enormously enlarged. 



* " The Trypanosome causing Disease in Man in Nyasaland. — Susceptibility of Animals 

 o the Human Strain," ' Eoy. Soc. Proc.,' B, vol. 87 (1913). 



