584 



Prof. T. G. Brodie. 



The diameter of the tubules was as follows : — 



ft. 



Proximal convoluted tubule — 



External diameter 44 - 8 48 - 



Lumen 13-0 19*8 



Distal convoluted tubule — 



External diameter 33-2 39*2 



Lumen 248 ' 29'2 



The expansion then is found in all parts, and is obviously brought about 

 by a distending force acting within the tubules. 



Yet another means of testing the theory which presented itself was to 

 observe the effect of obstructing the exit of urine down the ureter. In the 

 first set of experiments a diuresis was set up, and at its height the ureter on 

 one side was suddenly clamped. Five to fifteen minutes later the two kidneys 

 were exposed, their condition noted, and then the pedicles ligatured as close 

 as possible to the hilum. The kidneys were then removed and weighed. As 

 was to be expected, a kidney obstructed in this manner is very distended and 

 tense within its Capsule. The weights found in one experiment in which the 

 right kidney was obstructed at the height of diuresis, and the left secreting 



freely, were as follows : — 



grm. 



Weight of E. kidney 15 - 5 



„ L. kidney 13'5 



The right kidney was very tense, appeared almost bloodless, and was 

 distinctly lobulated. The left kidney was distinctly softer than the right 

 and also more vascular. The approximate volumes of the capsules and 



glomeruli were : — 



L. R 



Volume of capsule 86 146 



„ glomerulus 69 89 



fluid 17 57 



The measurements of the tubules were : — 



Proximal convoluted tubule — 



External diameter 39"2 39 - 4 



Lumen 6"6 14 - 



Distal convoluted tubule — 



External diameter 22*8 28*2 



Lumen 12-6 18*4 



