602 Prof. Brodie and Mr. Mackenzie. On Changes in the 



show corresponding differences. The effect as before is mainly felt in the 

 distal tubule, which shows a somewhat greater expansion. The lumina in 

 the proximal tubules are greater in the obstructed kidney than in the free 

 kidney. In this experiment the blood-pressure was rather low, but the 

 diuresis good. 



In all these obstructed kidneys the effect upon the medulla is very marked. 

 .Not only is the pelvis of the kidney greatly distended, but the pyramid is 

 driven back towards the cortex, and appears very much shrunken. We have 

 often seen it so contracted as to appear only about a quarter or less of its 

 normal size. In the sections the collecting tubules are flattened and empty, 

 the loops of Henle, however, contain fluid, and often appear to be about the 

 same size as in the normal active kidney. The appearance of the pyramids 

 is so characteristic that one can at once decide whether or no the ureter of 

 that kidney had been obstructed in the experiment. 



The last group of experiments comprises a comparison of various kidneys 

 with a kidney which was both obstructed and decapsulated. 



VII. Comparison of a Resting Kidney with a Decapsulated and Obstructed 



Kidney. 



Expt. 13. — E. kidney resting. L. kidney decapsulated and obstructed. 



Hence 





E. 



L. 







/*• 



Glomeruli and capsules — 









110-4 



128-0 





79-6 



110-8 





3-4 



21-2 





95-0 



119-4 





91-6 



98-2 





107 



213 



„ „ glomerulus 



96 



118 



fluid 



11 



95 



Convoluted tubules — 







Proximal. External diameter ... 



46-0 



49-6 





o-o 



26-4 



Distal. External diameter ... 



21-8 



34-4 





10-6 



24-4 





grm. 

 14-5 







19-3 





