282 



Miss D. J. Lloyd. 



internarconcentration is equivalent to 0*005 normal, and as this concentra- 

 tion is passed a certain amount of shrinkage follows. 



In distilled water, or in solutions of neutral salts, or in sugar solutions, 



300-r 



20O-- 



7/ro.ooo jVNA 



/oo\ 1 1 . 



/ 2. <3 <t ffJ's 



Fig. 3. 



Abscissae = time in hours from beginning of experiment. 



Ordinates = weight of muscle expressed in percentage of initial weight. 



Fig. 4. 



Abscissas = time in hours from beginning of experiment. 



Ordinates = weight of muscle expressed in percentage of initial weight. 



there may or may not be a preliminary gain in weight, but sooner or later 

 the muscle begins to coagulate, the fibres shorten, and the whole muscle 

 loses weight. This coagulation and loss of weight cannot be prevented by 

 any variation in the tonicity of the solution. The time-weight curves for 

 sugar solutions have already been published (7). The curves for the 

 chlorides of sodium, lithium, potassium, barium, calcium, in isotonic solutions, 

 are given in fig. 5. Following "Webster's precedent (26) - 125 molecular 

 solutions of the monovalent salts, and - 10 molecular solutions of the 

 divalent salts have been taken as isotonic. They all show the same changes, 

 but the coagulation appears much sooner in the solutions of the divalent 

 metals, while the initial rise in weight is strongly marked in the potassium, 



