294 



Prof. H. G. Plimmer. 



being ruptured in the preparation of the film, even with the greatest care. 

 The nucleus of the leucocyte invariably showed signs of hyperchromatosis, 

 often very marked. The nucleus of the parasite was often broken up into 

 granules, or chromidia, but many showed the single dot form with a clear 

 area around. Sometimes the Toxoplasma was found in the nucleus itself 

 (Plate 9, fig. 2). Schizonts were found in the bone-niarrow in various stages 

 up to the apparent breaking up into merozoits (Plate 9, fig. 3). Occasionally 

 the parasites were found in ■ the polynuclear cells in the bone-marrow : this 

 was possibly a phagocytic process, as the shapes of the ingested parasites 

 were much altered. 



II. Blue-tailed Fruit Pigeon, Carpophaga concinna,/?'om the Arte Islands. 



Plate 9, figs. 4-6 ; Plate 10, fig. 10. 



Died in an emaciated condition. The lungs were very congested, and 

 contained a large quantity of exudation. There was some bloody fluid in 

 the body cavity. Very few parasites were found in the blood, but large 

 numbers were present in the blood and exudation from the lungs. Some 

 were found free, but they were mostly contained in the large mononuclear 

 leucocytes. These cells had undergone more destruction than was the case 

 in the fossa, and the blood was extremely anaemic. The nucleus of the 

 Toxoplasma was generally single and definite, and was not broken up into 

 granules. A few were found in the bone-marrow, but none showing definite 

 schizogony. The drawing, reproduced in Plate 10, fig. 10, was made to scale 

 from an unfixed preparation, just tinted with 1-2000 methylene blue in - 8 per 

 cent, salt solution. At 1, there are ordinary forms of the Toxoplasma ; at 2, 

 a form with the nucleus in form of chromidia or granules ; at 3, a large 

 mononuclear leucocyte containing several parasites, some quite differentiated ; 

 and at 4, possibly an early stage of schizogony. 



III. Say's Snake, Coluber melanoleucus,/rom Mexico. Plate 10, figs. 7-9. 



The snake was very wasted, and its blood, which was very anaemic, 

 contained a few hsemogregarines. The lung was pneumonic and full of 

 exudation ; the liver was small and pale. Toxoplasmas were found in small 

 numbers in the exudation from the lung, and in enormous numbers in the 

 liver ; a few single ones in the blood. 



The above is all that it has been possible to find in this material. 

 A careful watch is being kept for new cases, from which it is hoped to 

 obtain material which will enable the knowledge of this curious parasite to 

 be carried further. 



