1879.] On Pep >sin- -forming Glands during ' Secretion. 385 



to restrict it. On his view it appears to us the border rather than 

 the central granules should be connected with the ferment. 



The Gastric Glands of the Newt (Triton Tseniatus). 



In the newt the glands were observed through the muscular coat of 

 the stomach, with a rapid capillary circulation still going on. 



Twenty-four hours after feeding, the glands of the fundus are 

 thickly granular throughout : about three hours after feeding, the 

 maximal change takes place ; it corresponds in the main to that 

 already described for the oesophageal glands of the frog. In the newt 

 the lumina and cell outlines become more conspicuous, the clear zone 

 is generally less sharply marked off from the granular zone ; and the 

 star arrangement of the granules is apparently only caused by the 

 presence of granules along the lateral margin of the cells after those 

 in the interior have disappeared. 



The glands recover their granular appearance comparatively quickly ; 

 in six hours after feeding, the granules have usually again crept up 

 to the periphery, they then increase in number throughout the cells 

 up to about the twenty-fourth hour. Later than this they diminish 

 somewhat, in six days the peripheries of the glands have become 

 more sparsely populated. It is at this period that digestion changes 

 are most readily observed. 



The pyloric glands are clear, or very finely granular, changes in 

 them would be much less conspicuous, in such observations as we 

 have made ; we have seen no difference in the hungry and digesting 

 states. 



In Triton cristatus the digestive changes are of the same nature, but 

 much less pronounced. 



The Gastric Glands of Stickleback (Gasteropodus trispinatus ?) 



We chose the stickleback mainly for its voracity, there is seldom 

 any difficulty in feeding it. 



In the gastric glands of the hungry fish, the granules thin away 

 somewhat from the centre to the periphery, the lumina are incon- 

 spicuous ; three to five hours after feeding the lumina are much 

 larger, the granules are aggregated about it leaving a peripheral clear 

 rim, the glands are more unequal in size, some having lost more 

 granules and diminished more in size than others. 



The Gastric Glands of Mammals. 



Examining in the fresh state, the glands of the fundus of the dog, cat, 

 or rat, we find that the body of each gland is marked out sharply into 

 two parts. A central part near the lnnien, consisting of many rather 

 large sharp granules, these granules form a central mass, which here 



